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organoid Easytag: an efficient workflow for gene targeting in human organoids

Dawei Sun, Lewis D. Evans, Emma L. Rawlins

Selected by Kirsty Ferguson

An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma

Rediet Zewdu, Elnaz Mirzaei Mehrabad, Kelley Ingram, et al.

Selected by Catherine Dabrowska

Differentiation of human intestinal organoids with endogenous vascular endothelial cells

Emily M. Holloway, Joshua H. Wu, Michael Czerwinkski, et al.

Selected by Nozomu Takata

TMPRSS2 and TMPRSS4 mediate SARS-CoV-2 infection of human small intestinal enterocytes

Ruochen Zang, Maria F.G. Castro, Broc T. McCune, et al.

Selected by Brooke Chambers

Early neurulation recapitulated in assemblies of embryonic and extraembryonic cells

Noémie M. L. P. Bérenger-Currias, Maria Mircea, Esmée Adegeest, et al.

Selected by Monica Tambalo

Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites

Jesse V Veenvliet, Adriano Bolondi, Helene Kretzmer, et al.

Selected by Martin Estermann

Constricted migration contributes to persistent 3D genome structure changes associated with an invasive phenotype in melanoma cells

Rosela Golloshi, Rebeca San Martin, Priyojit Das, et al.

Selected by Mariana De Niz

Tissue size controls patterns of cell proliferation and migration in freely-expanding epithelia

Matthew A. Heinrich, Julienne M. LaChance, Tom J. Zajdel, et al.

Selected by Mariana De Niz

Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites

Jesse V Veenvliet, Adriano Bolondi, Helene Kretzmer, et al.

Selected by Alok Javali

Defining totipotency using criteria of increasing stringency

Eszter Posfai, John Paul Schell, Adrian Janiszewski, et al.

Selected by Teresa Rayon

Patient-derived ovarian cancer organoids mimic clinical response and exhibit heterogeneous inter- and intrapatient drug responses

Chris J. de Witte, Jose Espejo Valle-Inclan, Nizar Hami, et al.

Selected by Zhang-He Goh

Identification of neural oscillations and epileptiform changes in human brain organoids

Ranmal A. Samarasinghe, Osvaldo A. Miranda, Simon Mitchell, et al.

Selected by Theresa Pohlkamp