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Temporal constraints on enhancer usage shape the regulation of limb gene transcription

Raquel Rouco, Antonella Rauseo, Guillaume Sapin, et al.

OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide

Hugo Sepulveda, Xiang Li, Xiaojing Yue, et al.

Transcriptional profiling of human brain cortex identifies novel lncRNA-mediated networks dysregulated in amyotrophic lateral sclerosis

Alessandro Palma, Monica Ballarino

Clusters of lineage-specific genes are anchored by ZNF274 in repressive perinucleolar compartments

Martina Begnis, Julien Duc, Sandra Offner, et al.

A long non-coding RNA at the cortex locus controls adaptive colouration in butterflies

Luca Livraghi, Joseph J. Hanly, Elizabeth Evans, et al.

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The ivory lncRNA regulates seasonal color patterns in buckeye butterflies

Richard A. Fandino, Noah K. Brady, Martik Chatterjee, et al.

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A micro-RNA drives a 100-million-year adaptive evolution of melanic patterns in butterflies and moths

Shen Tian, Tirtha Das Banerjee, Jocelyn Liang Qi Wee, et al.

Single-cell epigenomic reconstruction of developmental trajectories in human neural organoid systems from pluripotency

Fides Zenk, Jonas Simon Fleck, Sophie Martina Johanna Jansen, et al.

LincRNAs enable germ cells differentiation by promoting PUF proteins condensation

Roni Falk, Noa Gilad, Hanna Achache, et al.

Biologically informed NeuralODEs for genome-wide regulatory dynamics

Intekhab Hossain, Viola Fanfani, John Quackenbush, et al.

A data-driven Boolean model explains memory subsets and evolution in CD8+ T cell exhaustion

Geena V. Ildefonso, Stacey D. Finley

Deterministic and probabilistic fate decisions co-exist in a single retinal lineage

Elisa Nerli, Jenny Kretzschmar, Tommaso Bianucci, et al.

Synthetic memory circuits for programmable cell reconfiguration in plants

James P B Lloyd, Florence Ly, Patrick Gong, et al.

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Synthetic genetic circuits enable reprogramming of plant roots

Jennifer A. N. Brophy, Katie J. Magallon, Kiril Kniazev, et al.

Increased gene dosage and mRNA expression from chromosomal duplications in C. elegans

Bhavana Ragipani, Sarah Elizabeth Albritton, Ana Karina Morao, et al.