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Cryo-EM reveals multiple mechanisms of ribosome inhibition by doxycycline

William S. Stuart, Michail N. Isupov, Mathew McLaren, et al.

Selected by 06 January 2026

Leonie Brüne

Molecular Biology

In vitro pharmacokinetics and pharmacodynamics of the diarylquinoline TBAJ-587 and its metabolites against Mycobacterium tuberculosis

Diana Angelica Aguilar-Ayala, Marie Sylvianne Rabodoarivelo, Maxime R. Eveque-Mourroux, et al.

Selected by 24 November 2025

Zhang-He Goh

Pharmacology and Toxicology

RNA Structure Directs RNA Partitioning and is Actively Disrupted inside Stress Granules to Enable Cellular Recovery

Bowen Zhu, Jovi Jian An Lim, Yu Zhang, et al.

Selected by 25 September 2025

Mohammed JALLOH

Molecular Biology

tRNA synthetase activity is required for stress granule and P-body assembly

Max Baymiller, Noah S. Helton, Benjamin Dodd, et al.

Selected by 19 May 2025

Mohammed JALLOH

Molecular Biology

Chronic stress antagonizes formation of Stress Granules

Yuichiro Adachi, Allison M. Williams, Masashi Masuda, et al.

Selected by 08 April 2025

Mohammed JALLOH

Cell Biology

Intracellular diffusion in the cytoplasm increases with cell size in fission yeast

Catherine Tan, Michael C. Lanz, Matthew Swaffer, et al.

Selected by 18 October 2024

Leeba Ann Chacko, Sameer Thukral

Cell Biology

Hibernating ribosomes tether to mitochondria as an adaptive response to cellular stress during glucose depletion

Olivier Gemin, Maciej Gluc, Michael Purdy, et al.

Selected by 15 November 2023

Barbora Knotkova

Molecular Biology

Quantification of gallium cryo-FIB milling damage in biological lamella

Bronwyn A. Lucas, Nikolaus Grigorieff

Selected by 08 March 2023

Kanika Khanna

Biophysics

A specialized mRNA translation circuit instated in pluripotency presets the competence for cardiogenesis in humans

Deniz Bartsch, Kaustubh Kalamkar, Gaurav Ahuja, et al.

Selected by 02 November 2022

Emma Armitage

Dissecting aneuploidy phenotypes by constructing Sc2.0 chromosome VII and SCRaMbLEing synthetic disomic yeast

Yue Shen, Feng Gao, Yun Wang, et al.

Selected by 17 October 2022

Grace Thomas

Cell Biology

Absolute Scaling of Single-Cell Transcriptomes Reveals Pervasive Hypertranscription in Adult Stem and Progenitor Cells

Yun-Kyo Kim, Miguel Ramalho-Santos

Selected by 29 March 2022

Vanessa Luzak

Molecular Biology

High-throughput aminoacyl-tRNA synthetase engineering for genetic code expansion in yeast

Jessica T. Stieglitz, James A. Van Deventer

Selected by 23 December 2021

Zhang-He Goh

Bioengineering