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Targeting CXADR-mediated AKT signaling suppresses tumorigenesis and enhances chemotherapy efficacy in Ewing sarcoma

Alina Ritter, Malenka Zimmermann, Florian H. Geyer, et al.

Discussion

Dual inhibition of GTP-bound (ON) and GDP-bound (OFF) KRAS^G12C suppresses PI3Kα and leads to potent tumor inhibition

Katherine Parker, Samar Ghorbanpoor, Wafa Malik, et al.

Discussion

Ribosome Molecular Aging Shapes translation Dynamics

Jordy F. Botello, Lifei Jiang, Peter J. Metzger, et al.

Discussion

The metabolome and proteome of stem cell-derived human primordial germ cells: a multi-omics approach

Madalena Vaz Santos, Bauke V. Schomakers, Llobet Ayala Marta, et al.

Prenatal Stress Differentially Shapes Adult Behavior in Male and Female Offspring

Erbo Dong, Alison Chu, Tamar Gur, et al.

Discussion

UFMylation of Pyruvate Dehydrogenase Regulates Mitochondrial Metabolism

Phong T. Nguyen, Zheng Wu, Dohun Kim, et al.

Detergent-Triggered Membrane Remodelling Monitored via Intramembrane Fluorescence De-Quenching

Claudia M. F. Andrews, Christopher M. Hofmair, Lauryn Roberts, et al.

Discussion

A thirty-year trend of increasing clinical orientation at the National Institutes of Health

Brad L. Busse, James M. Tucker, Summer E. Allen, et al.

AND

Prediction of transformative breakthroughs in biomedical research

Matthew T. Davis, Brad L. Busse, Salsabil Arabi, et al.

Self-renewal of neuronal mitochondria through asymmetric division

Tejashree Pradip Waingankar, Camryn Zurita, Angelica E. Lang, et al.

Active flows drive clustering and sorting of membrane components with differential affinity to dynamic actin cytoskeleton

Abrar Bhat, Amit Das, Meenakshi Iyer, et al.

A Novel Chimeric Antigen Receptor (CAR) - Strategy to Target EGFRVIII-Mutated Glioblastoma Cells via Macrophages

Kristi Vera, Gülen Esken, Jin Wook Hwang, et al.

Discussion

Cryo-EM reveals multiple mechanisms of ribosome inhibition by doxycycline

William S. Stuart, Michail N. Isupov, Mathew McLaren, et al.