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Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies

Candice Gurbatri, Courtney Coker, Taylor E. Hinchliffe, et al.

AND

Programmable bacteria induce durable tumor regression and systemic antitumor immunity

Sreyan Chowdhury, Taylor E Hinchliffe, Samuel Castro, et al.

Discussion

Mitotic exit is controlled during anaphase by an Aurora B-Cyclin B1/Cdk1 crosstalk

Olga Afonso, Liam P. Cheeseman, Luísa T. Ferreira, et al.

Human DNA-PK activates a STING-independent DNA sensing pathway

Katelyn Burleigh, Joanna H. Maltbaek, Stephanie Cambier, et al.

Discussion

A Bile Duct-on-a-Chip with Organ-Level Functions

Yu Du, Gauri Khandekar, Jessica Llewellyn, et al.

Preformed Chromatin Topology Assists Transcriptional Robustness of Shh during Limb Development

Christina Paliou, Philine Guckelberger, Robert Schöpflin, et al.

A unicellular relative of animals generates an epithelium-like cell layer by actomyosin-dependent cellularization

Omaya Dudin, Andrej Ondracka, Xavier Grau-Bové, et al.

Over-activation of BMP signaling in neural crest cells precipitates heart outflow tract septation

Jean Francois Darrigrand, Mariana Valente, Pauline Martinez, et al.

Discussion

Blue light induces neuronal-activity-regulated gene expression in the absence of optogenetic proteins

Kelsey M. Tyssowski, Jesse M. Gray

Discussion

Crowdfunded whole-genome sequencing of the celebrity cat Lil BUB identifies causal mutations for her osteopetrosis and polydactyly

Mike Bridavsky, Heiner Kuhl, Arthur Woodruf, et al.

Slide-seq: A Scalable Technology for Measuring Genome-Wide Expression at High Spatial Resolution

Samuel G Rodriques, Robert R Stickels, Aleksandrina Goeva, et al.

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High-density spatial transcriptomics arrays for in situ tissue profiling

Sanja Vickovic, Goekcen Eraslan, Johanna Klughammer, et al.

Discussion

Multi-immersion open-top light-sheet microscope for high-throughput imaging of cleared tissues

Adam K. Glaser, Nicholas P. Reder, Ye Chen, et al.

ATAT1-enriched vesicles promote microtubule acetylation via axonal transport

Aviel Even, Giovanni Morelli, Chiara Scaramuzzino, et al.