I hold a Violette and Samuel Glasstone Independent Research Fellow in the Department of Plant Sciences at the University of Oxford. My research is focussed on developing and applying synthetic biology approaches to the Euglenozoa, a monophylletic group including both free living algae and parasitic eukaryotes. I am taking a multidisciplinary approach to establish metabolic capacity and utility of different species in this group. This includes developing transformation protocols, characterising metabolic capacity and applying high-throughput sequencing approaches for novel pathway discovery. These disparate approaches are used to facilitate targeted engineering of complex metabolic pathways for the production of compounds for industrial, biotechnology and medicinal applications.
Proteome of the secondary plastid of Euglena gracilis reveals metabolic quirks and colourful history
Glutamic acid is a carrier for hydrazine during the biosyntheses of fosfazinomycin and kinamycin
Peculiar features of the plastids of the colourless alga Euglena longa and photosynthetic euglenophytes unveiled by transcriptome analyses
Marionette: E. coli containing 12 highly-optimized small molecule sensors
Mitochondrial targeting of glycolysis in a major lineage of eukaryotes.