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Ellis O'Neill

University of Oxford

I hold a Violette and Samuel Glasstone Independent Research Fellow in the Department of Plant Sciences at the University of Oxford. My research is focussed on developing and applying synthetic biology approaches to the Euglenozoa, a monophylletic group including both free living algae and parasitic eukaryotes. I am taking a multidisciplinary approach to establish metabolic capacity and utility of different species in this group. This includes developing transformation protocols, characterising metabolic capacity and applying high-throughput sequencing approaches for novel pathway discovery. These disparate approaches are used to facilitate targeted engineering of complex metabolic pathways for the production of compounds for industrial, biotechnology and medicinal applications.

Ellis O'Neill has added 5 preLight posts

Proteome of the secondary plastid of Euglena gracilis reveals metabolic quirks and colourful history

Anna M. G. Novák Vanclová, Martin Zoltner, Steven Kelly, et al.

Selected by 20 March 2019

Ellis O'Neill

Glutamic acid is a carrier for hydrazine during the biosyntheses of fosfazinomycin and kinamycin

Kwo-Kwang Abraham Wang, Tai L. Ng, Peng Wang, et al.

Selected by 19 July 2018

Ellis O'Neill

Biochemistry

Peculiar features of the plastids of the colourless alga Euglena longa and photosynthetic euglenophytes unveiled by transcriptome analyses

Kristina Zahonova, Zoltan Fussy, Erik Bircak, et al.

Selected by 11 July 2018

Ellis O'Neill

Cell Biology

Marionette: E. coli containing 12 highly-optimized small molecule sensors

Adam J. Meyer, Thomas H. Segall-Shapiro, Christopher A Voigt

Selected by 05 April 2018

Ellis O'Neill

Mitochondrial targeting of glycolysis in a major lineage of eukaryotes.

Carolina Río Bártulos, Matthew B. Rogers, Tom A. Williams , et al.

Selected by 13 February 2018

Ellis O'Neill

Biochemistry

Ellis O'Neill has commented 2 times

6 years

Ellis O'Neill

Thanks for your comments – the timing sounds a particularly interesting use. I can imagine expressing a set of enzymes later in a pathway before allowing the first steps, to make sure there is no build up of intermediates.

6 years

Ellis O'Neill

Thanks for your comments – the timing sounds a particularly interesting use. I can imagine expressing a set of enzymes later in a pathway before allowing the first steps, to make sure there is no build up of intermediates.

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