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Emma Wilson

My research focuses on understanding neurodegeneration, specifically investigating mitochondrial quality control and its role in the mechanisms of Parkinson’s Disease.  I conducted my PhD in the Whitworth and De Vos Labs at the University of Sheffield, here I investigated the role of phosphatidylinositols in mitophagy and mitochondrial morphology, using Drosophila models. During this time, I expanded my interest to encompass Mitochondria ER-Contact sites (MERCS) and I developed a split fluorescence protein system which can be used to visualise MERCS. I currently work in the Metzakopian lab within the Dementia Research Institute (DRI) at the University of Cambridge, developing an induced pluripotent stem cells (IPSC) differentiation protocol to generate enteric neurones; these cells can be used in high-throughput CRISPR/Cas9 screen to examine novel genes associated with Parkinson’s Disease. I have also continued my work on MERCS, combining CRISPR/Cas9 screening and split florescent proteins-based system to investigate novel genes involved with MERCS modulation.

Beyond this, I am interested in ‘open science’ and Early Career Research (ECR) development. I am a DRI ECR representative and I’m organising mentoring schemes, social activities and ongoing ECR-focused talks. Outside of science, I am a keen runner, training towards a half marathon and also a skilled Jitsuka, looking to achieve my instructor belt in the coming months.

Emma Wilson has added 4 preLight posts

Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality

Sonia Sabate-Soler, Sarah Louise Nickels, Cláudia Saraiva, et al.

Selected by 08 March 2022

Emma Wilson

Neuroscience

Tau assemblies enter the cytosol of neurons in a cholesterol sensitive manner

Benjamin J. Tuck, Taxiarchis Katsinelos, Lauren V. C. Miller, et al.

Selected by 07 July 2021

Emma Wilson

Neuroscience

Citation needed? Wikipedia and the COVID-19 pandemic

Omer Benjakob, Rona Aviram, Jonathan Sobel

Selected by 05 July 2021

Emma Wilson, Jonny Coates

Scientific Communication and Education

Novel insights in the pathophysiology of α-synuclein dysregulation on D2 receptor activity contributing to the vulnerability of dopamine neurons

Abeer Dagra, Douglas R. Miller, Fatemeh Shaerzadeh, et al.

Selected by 26 May 2021

Emma Wilson

Neuroscience

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