I am currently a Postdoctoral Fellow at the Wellcome Trust Sanger Institute, Cambridge, UK as part of their new Synthetic Genomics Group.
Previously, I was based at the Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria. I studied the interactome of leukaemia-associated fusion oncogenes through mass spectrometry and CRISPR/Cas9. I completed my undergraduate degree in Genetics at Queen’s University Belfast in Northern Ireland. After a short, but incredibly useful, spell in industry I began a PhD at the Centre for Cancer Research and Cell Biology in Belfast. In the lab of Prof. Ken Mills, I used bioinformatic analysis to understand the transcriptional changes involved in myelodysplastic syndrome development. My Postdoc there developed genetic models of SF3B1 gene mutation using CRISPR/Cas9.
Whether to understand human disease or basic biology, my passion lies in testing and developing new additions to the increasingly powerful genome engineering toolbox.
Drag-and-drop genome insertion without DNA cleavage with CRISPR-directed integrases
Louise Moyle et al.
Precise genomic deletions using paired prime editing
Fabio Liberante
Template switching causes artificial junction formation and false identification of circular RNAs
Fabio Liberante