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Jade Chan

University of Toronto/SickKids Research Institute

I am a PhD student co-supervised by Dr. Xi Huang and Dr. C.C. Hui at SickKids Research Institute in Toronto, Canada. My lab is interested in dissecting the roles of ion channels and tissue mechanics in the development of adult and pediatric brain tumours. Specifically, I am investigating the function of a potassium channel protein in medulloblastoma, one of the most common malignant brain cancers in children.

I am happy to share interesting and exciting new preprints on topics including but not limited to mechanosensation, cell migration, and cancer neuroscience!

Jade Chan has added 8 preLight posts

Invasion of glioma cells through confined space requires membrane tension regulation and mechano-electrical coupling via Plexin-B2

Chrystian Junqueira Alves, Theodore Hannah, Sita Sadia, et al.

Selected by 13 February 2024

Jade Chan

Cancer Biology

2D and 3D multiplexed subcellular profiling of nuclear instability in human cancer

Shannon Coy, Brian Cheng, Jong Suk Lee, et al.

Selected by 22 December 2023

Jade Chan

Cancer Biology

Small extracellular vesicles promote stiffness-mediated metastasis

Alexandra Sneider, Ying Liu, Bartholomew Starich, et al.

Selected by 03 August 2023

Jade Chan, yohalie kalukula

Cancer Biology

Glioblastoma extracellular vesicles influence glial cell hyaluronic acid deposition to promote invasiveness

Dominik Koessinger, David Novo, Anna Koessinger, et al.

Selected by 13 June 2023

Jade Chan

Cancer Biology

Functional synapses between small cell lung cancer and glutamatergic neurons

Anna Schmitt, Vignesh Sakthivelu, Kristiano Ndoci, et al.

Selected by 13 February 2023

Jade Chan

Cancer Biology

Proteolysis-free cell migration through crowded environments via mechanical worrying

Meghan K. Driscoll, Erik S. Welf, Andrew Weems, et al.

Selected by 05 December 2022

Jade Chan

Cell Biology

An Arp2/3-cPLA2-NFκB axis acts as a Cell Shape Sensor to drive Homeostatic Migration of Dendritic Cells

Zahraa Alraies, Claudia A. Rivera, Maria-Graciela Delgado, et al.

Selected by 03 October 2022

Jade Chan

Cell Biology

Mechanosensitive dynamics of lysosomes regulates the emergence of leader cells during collective cell migration

Rituraj Marwaha, Simran Rawal, Purnati Khuntia, et al.

Selected by 12 September 2022

Jade Chan

Cell Biology

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