I am a PhD student co-supervised by Dr. Xi Huang and Dr. C.C. Hui at SickKids Research Institute in Toronto, Canada. My lab is interested in dissecting the roles of ion channels and tissue mechanics in the development of adult and pediatric brain tumours. Specifically, I am investigating the function of a potassium channel protein in medulloblastoma, one of the most common malignant brain cancers in children.
I am happy to share interesting and exciting new preprints on topics including but not limited to mechanosensation, cell migration, and cancer neuroscience!
Small extracellular vesicles promote stiffness-mediated metastasis
Glioblastoma extracellular vesicles influence glial cell hyaluronic acid deposition to promote invasiveness
Functional synapses between small cell lung cancer and glutamatergic neurons
Proteolysis-free cell migration through crowded environments via mechanical worrying
An Arp2/3-cPLA2-NFκB axis acts as a Cell Shape Sensor to drive Homeostatic Migration of Dendritic Cells
Mechanosensitive dynamics of lysosomes regulates the emergence of leader cells during collective cell migration