Preprint highlights, selected by the biological community
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I am currently Instructor at UT Southwestern in Dallas, where I started my postdoc in 2013 in the Herz Lab working on endosomal trafficking of Apolipoprotein E (ApoE) isoforms to understand the mechanism how ApoE4 contributes to Alzheimer’s disease. I finished my PhD in 2012 in the field of Neuroscience at the University of Freiburg, Germany, my thesis focused on the extracellular glycoprotein Reelin that signals through ApoE receptors to control neuronal migration, maturation, and plasticity. Before I focused on neuroscience I did my undergraduate in Biology at the University of Münster, Germany, where I studied blood coagulation for my diploma thesis. Besides bench work and science writing I love to ride the bicycle!
Integrative Brain Transcriptome Analysis Links Complement Component 4 and HSPA2 to the APOE ε2 Protective Effect in Alzheimer Disease
| Selected by | Theresa Pohlkamp |
Transient Maternal IL-6 boosts glutamatergic synapses and disrupts hippocampal connectivity in the offspring
| Selected by | Theresa Pohlkamp |
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SARS-CoV-2 infects brain choroid plexus and disrupts the blood-CSF-barrier
| Selected by | Theresa Pohlkamp |
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Oligodendrocyte-derived exosomes promote axonal transport and axonal long-term maintenance
| Selected by | Theresa Pohlkamp |
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The Rab5-Rab11 endosomal pathway is required for BDNF-induced CREB transcriptional regulation in neurons
| Selected by | Theresa Pohlkamp |
Identification of neural oscillations and epileptiform changes in human brain organoids
| Selected by | Theresa Pohlkamp |
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Cholesterol and matrisome pathways dysregulated in human APOE ε4 glia
| Selected by | Theresa Pohlkamp |
2
NEUROD2 represses Reelin expression and controls dendrite orientation during cortical radial migration
| Selected by | Theresa Pohlkamp |
2 years
Theresa Pohlkamp
I am very excited for the authors! The paper is now available on the SneakPeek server of Cell:
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3435267
It does contain additional data, especially in the last figure!