Generative modeling of single-cell population time series for inferring cell differentiation landscapes

Grace H.T. Yeo, Sachit D. Saksena, David K. Gifford

Discussion

A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic

Maria Alimova, Eriene-Heidi Sidhom, Abhigyan Satyam, et al.

AND

Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses

Willianne Hoepel, Hung-Jen Chen, Sona Allahverdiyeva, et al.

Discussion

Molecular Logic of Spinocerebellar Tract Neuron Diversity and Connectivity

Myungin Baek, Vilas Menon, Thomas Jessell, et al.

Discussion

Lineage tracing on transcriptional landscapes links state to fate during differentiation

Caleb Weinreb, Alejo E Rodriguez-Fraticelli, Fernando D Camargo, et al.

Maintenance of spatial gene expression by Polycomb-mediated repression after formation of a vertebrate body plan

Julien Rougot, Naomi D Chrispijn, Marco Aben, et al.

SABER enables highly multiplexed and amplified detection of DNA and RNA in cells and tissues

Jocelyn Y. Kishi, Brian J. Beliveau, Sylvain W. Lapan, et al.

Discussion

LCM-seq reveals unique transcriptional adaption mechanisms of resistant neurons in spinal muscular atrophy

Susanne Nichterwitz, Helena Storvall, Jik Nijssen, et al.

AND

Axon-seq decodes the motor axon transcriptome and its modulation in response to ALS

Jik Nijssen, Julio Cesar Aguila Benitez, Rein Hoogstraaten, et al.

Discussion

Fbxw7 is a critical regulator of Schwann cell myelinating potential

Breanne L Harty, Fernanda Coelho, Sarah D Ackerman, et al.

Discussion