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An intermembrane space protein facilitates completion of mitochondrial division in yeast

Olivia M. Connor, Srujan K. Matta, Jonathan R. Friedman

Cell polarity linked to gravity sensing is generated by protein translocation from statoliths to the plasma membrane

Takeshi Nishimura, Shogo Mori, Hiromasa Shikata, et al.

AND

Amyloplast sedimentation repolarizes LAZYs to achieve gravity sensing in plants

Jiayue Chen, Renbo Yu, Na Li, et al.

Spatial and single-cell transcriptomics reveal neuron-astrocyte interplay in long-term memory

Wenfei Sun, Zhihui Liu, Xian Jiang, et al.

Discussion

ProteasomeID: quantitative mapping of proteasome interactomes and substrates for in vitro and in vivo studies

Aleksandar Bartolome, Julia C. Heiby, Therese Dau, et al.

Discussion

Inhibition of Centrosome Clustering Reduces Cystogenesis and Improves Kidney Function in Autosomal Dominant Polycystic Kidney Disease

Tao Cheng, Aruljothi Mariappan, Ewa Langner, et al.

Massively parallel protein-protein interaction measurement by sequencing (MP3-seq) enables rapid screening of protein heterodimers

Alexander Baryshev, Alyssa La Fleur, Benjamin Groves, et al.

actin nucleators safeguard replication forks by limiting nascent strand degradation

Jadwiga Nieminuszczy, Peter R. Martin, Ronan Broderick, et al.

Discussion

marmite defines a novel conserved neuropeptide family mediating nutritional homeostasis

AP Francisco, I Tastekin, AB Fernandes, et al.

Discussion

Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment

Julia Kolb, Nora John, Kyoohyun Kim, et al.

3D genome organization around nuclear speckles drives mRNA splicing efficiency

Prashant Bhat, Amy Chow, Benjamin Emert, et al.

Functional synapses between small cell lung cancer and glutamatergic neurons

Anna Schmitt, Vignesh Sakthivelu, Kristiano Ndoci, et al.

Discussion

VAP spatially stabilizes dendritic mitochondria to locally fuel synaptic plasticity

Ojasee Bapat, Tejas Purimetla, Sarah Kruessel, et al.