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Basal extrusion drives cell invasion and mechanical stripping of E-cadherin

John Fadul, Gloria M Slattum, Nadja M Redd, et al.

Discussion

The modular mechanism of chromocenter formation in Drosophila

Madhav Jagannathan, Ryan Cummings, Yukiko M Yamashita

The Toll pathway inhibits tissue growth and regulates cell fitness in an infection-dependent manner

Federico Germani, Daniel Hain, Denise Sternlicht, et al.

Discussion

Rapid embryonic cell cycles defer the establishment of heterochromatin by Eggless/SetDB1 in Drosophila

Charles A Seller, Chun-Yi Cho, Patrick H O'Farrell

Discussion

PUMILIO hyperactivity drives premature aging of Norad-deficient mice

Florian Kopp, Mehmet Yalvac, Beibei Chen, et al.

Discussion

Synergy with TGFβ ligands switches WNT pathway dynamics from transient to sustained during human pluripotent cell differentiation

Joseph Massey, Yida Liu, Omar Alvarenga, et al.

LCM-seq reveals unique transcriptional adaption mechanisms of resistant neurons in spinal muscular atrophy

Susanne Nichterwitz, Helena Storvall, Jik Nijssen, et al.

AND

Axon-seq decodes the motor axon transcriptome and its modulation in response to ALS

Jik Nijssen, Julio Cesar Aguila Benitez, Rein Hoogstraaten, et al.

Discussion

Aurora A depletion reveals centrosome-independent polarization mechanism in C. elegans

Kerstin Klinkert, Nicolas Levernier, Peter Gross, et al.

AND

Centrosome Aurora A gradient ensures a single PAR-2 polarity axis by regulating RhoGEF ECT-2 localization in C. elegans embryos

Sachin Kotak, Sukriti Kapoor

LADL: Light-activated dynamic looping for endogenous gene expression control

Mayuri Rege, Ji Hun Kim, Jacqueline Valeri, et al.

Discussion

A cell cycle-coordinated nuclear compartment for Polymerase II transcription encompasses the earliest gene expression before global genome activation

Yavor Hadzhiev, Haseeb Qureshi, Lucy Wheatley, et al.

Nuclear pore density controls heterochromatin reorganization during senescence

Charlene Boumendil, Priya Hari, Karl Olsen, et al.

The Histone H3-H4 Tetramer is a Copper Reductase Enzyme

Narsis Attar, Oscar A Campos, Maria Vogelauer, et al.

Discussion