Search results

Correction of Niemann-Pick type C1 disease with the histone deacetylase inhibitor valproic acid

Kanagaraj Subramanian, Darren M Hutt, Vijay Gupta, et al.

Selected by 17 September 2019

Joanna Cross

Discussion

Single-cell gene regulatory network analysis reveals new melanoma cell states and transition trajectories during phenotype switching

Jasper Wouters, Zeynep Kalender-Atak, Liesbeth Minnoye, et al.

Selected by 13 September 2019

Hannah Brunsdon

Discussion

Hypoxia induces transcriptional and translational downregulation of the type I interferon (IFN) pathway in multiple cancer cell types

Ana Miar, Esther Arnaiz, Esther Bridges, et al.

Selected by 25 August 2019

Jonny Coates

Discussion

Engineering Phage Host-Range and Suppressing Bacterial resistance Through Phage Tail Fiber Mutagenesis

Kevin Yehl, Sébastien Lemire, Andrew C. Yang, et al.

Selected by 27 July 2019

Zhang-He Goh

Discussion

Cross-kingdom recognition of bacterial small RNAs induces transgenerational pathogenic avoidance

Rachel Kaletsky, Rebecca S. Moore, Lance L. Parsons, et al.

Selected by 27 July 2019

Madhuja Samaddar

TGFβ restricts T cell function and bacterial control within the tuberculous granuloma

Benjamin H Gern, Kristin N Adams, Courtney R Plumlee, et al.

Selected by 26 July 2019

Kasturi MAHADIK

Discussion

The origin of extracellular DNA in bacterial biofilm infections in vivo

Maria Alhede, Morten Alhede, Klaus Qvortrup, et al.

Selected by 22 July 2019

Snehal Kadam

Discussion

Gene regulatory network inference and analysis of multidrug-resistant Pseudomonas aeruginosa

Fernando Medeiros Filho, Ana Paula Barbosa do Nascimento, Marcelo Trindade dos Santos, et al.

Selected by 19 July 2019

Euan McDonnell

Discussion

Elucidating the molecular determinants of Aβ aggregation with deep mutational scanning

Vanessa E Gray, Katherine Sitko, Floriane Z. Ngako Kameni, et al.

Selected by 18 July 2019

Suzanne McDermott

Discussion

Modulation of neuronal resilience during aging by Hsp70/Hsp90/STI1 chaperone system

Rachel Lackie, Abdul Razzaq, Sali M.K. Farhan, et al.

Selected by 12 June 2019

Giuliana Clemente

Antimicrobials: Discovery, clinical use, and development of resistance

Preprints that describe the discovery of new antimicrobials and any improvements made regarding their clinical use. Includes preprints that detail the factors affecting antimicrobial selection and the development of antimicrobial resistance.

 

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Zhang-He Goh

Spontaneous isomerization of long-lived proteins provides a molecular mechanism for the lysosomal failure observed in Alzheimer’s disease

Tyler R. Lambeth, Dylan L. Riggs, Lance E. Talbert, et al.

Selected by 15 May 2019

Joanna Cross

Discussion