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Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis

Ruilin Tian, Anthony Abarientos, Jason Hong, et al.

Toll-like receptor 4 is activated by platinum and contributes to cisplatin-induced ototoxicity

Ghazal Babolmorad, Asna Latif, Niall M. Pollock, et al.

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Application of the in vivo oxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity

Francisco Inesta-Vaquera, Panida Navasumrit, Colin J. Henderson, et al.

Severe immunodeficiency in mice lacking DNA repair factors XLF and Mri

Sergio Castañeda-Zegarra, Qindong Zhang, Amin Alirezaylavasani, et al.

Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival

Paolo Armando Gagliardi, Maciej Dobrzyński, Marc-Antoine Jacques, et al.

A hydraulic instability drives the cell death decision in the nematode germline

N. T. Chartier, A. Mukherjee, J. Pfanzelter, et al.

PINK1 and parkin shape the organism-wide distribution of a deleterious mitochondrial genome

Arnaud Ahier, Nadia Cummins, Chuan-Yang Dai, et al.

Mitophagy protects beta cells from inflammatory damage in diabetes

Vaibhav Sidarala, Gemma L. Pearson, Vishal S. Parekh, et al.

EllipTrack: A Global-Local Cell-Tracking Pipeline for 2D Fluorescence Time-Lapse Microscopy

Chengzhe Tian, Chen Yang, Sabrina L. Spencer

Transplantation of Muscle Stem Cell Mitochondria Rejuvenates the Bioenergetic Function of Dystrophic Muscle

Mahir Mohiuddin, Jeongmoon J. Choi, et al.

Single-cell longitudinal analysis of SARS-CoV-2 infection in human bronchial epithelial cells

Neal G. Ravindra, Mia Madel Alfajaro, Victor Gasque, et al.

Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance

Anne Ramsay Bowden, David A. Morales Juarez, Matylda Sczaniecka-Clift, et al.

Robustness of epithelial sealing is an emerging property of local ERK feedbacks driven by cell elimination

Léo Valon, Florence Levillayer, Anđela Davidović, et al.