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Selective K-ATP channel-dependent loss of pacemaking in vulnerable nigrostriatal dopamine neurons by α-synuclein aggregates

Poonam Thakur, Kelvin Luk, Jochen Roeper

Selected by 18 December 2019

Jessica Xie

Neuroscience

Identification of neural oscillations and epileptiform changes in human brain organoids

Ranmal A. Samarasinghe, Osvaldo A. Miranda, Simon Mitchell, et al.

Selected by 25 November 2019

Theresa Pohlkamp

Neuroscience

Senescence of alveolar stem cells drives progressive pulmonary fibrosis

Changfu Yao, Xiangrong Guan, Gianni Carraro, et al.

Selected by 08 November 2019

Rob Hynds

Cell Biology

Colibactin DNA damage signature indicates causative role in colorectal cancer

Paulina J. Dziubańska-Kusibab, Hilmar Berger, Federica Battistini, et al.

Selected by 01 November 2019

Connor Rosen

Microbiology

A deeper understanding of intestinal organoid metabolism revealed by combining fluorescence lifetime imaging microscopy (FLIM) and extracellular flux analyses

Irina A. Okkelman, Nuno Neto, Dmitri B. Papkovsky, et al.

Selected by 30 October 2019

Jessica Xie

Cell Biology

Hif-1alpha stabilisation is protective against infection in a zebrafish model of comorbidity

Yves Schild, Abdirizak Mohamed, Edward J. Wootton, et al.

Selected by 28 October 2019

Jonny Coates

Immunology

HSP110 dependent HSP70 disaggregation machinery mediates prion-like propagation of amyloidogenic proteins in metazoa

Jessica Tittelmeier, Carl Alexander Sandhof, Heidrun Maja Ries, et al.

Selected by 27 October 2019

Tessa Sinnige

Coexistence with Pseudomonas aeruginosa alters Staphylococcus aureus transcriptome, antibiotic resistance and internalization into epithelial cells

Paul Briaud, Laura Camus, Sylvère Bastien, et al.

Selected by 22 October 2019

Sharmada Swaminath

Microbiology

The enteric nervous system of the human and mouse colon at a single-cell resolution

Eugene Drokhlyansky, Christopher S. Smillie, Nicholas Van Wittenberghe, et al.

Selected by 07 October 2019

Jessica Xie

Genomics

Single Cell Gene Expression Analysis Reveals Human Stem Cell-Derived Graft Composition in a Cell Therapy Model of Parkinson’s disease

Katarína Tiklová, Sara Nolbrant, Alessandro Fiorenzano, et al.

Selected by 27 September 2019

Jessica Xie

Neuroscience

The properties of α-synuclein secondary nuclei are dominated by the solution conditions rather than the seed fibril strain

Alessia Peduzzo, Sara Linse, Alexander K. Buell

Selected by 20 September 2019

Tessa Sinnige

Biophysics

Single-cell RNA-sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis

Arun C. Habermann, Austin J. Gutierrez, Linh T. Bui, et al.

AND

Single Cell RNA-seq reveals ectopic and aberrant lung resident cell populations in Idiopathic Pulmonary Fibrosis

Taylor S. Adams, Jonas C. Schupp, Sergio Poli, et al.

Selected by 20 September 2019

Rob Hynds

Cell Biology