Intestinal peroxisomal fatty acid β-oxidation regulates neural serotonin signaling through a feedback mechanism
Selected by
Pablo Ranea Robles
Spontaneous isomerization of long-lived proteins provides a molecular mechanism for the lysosomal failure observed in Alzheimer’s disease
Selected by
Joanna Cross
Specific Disruption of Established P. aeruginosa Biofilms Using Polymer-Attacking enzymes
Selected by
Snehal Kadam
Tousled-like kinase activity is required for transcriptional silencing and suppression of innate immune signaling
Selected by
Yasmin Lau
Accurate detection of m6A RNA modifications in native RNA sequences
Selected by
Christian Bates
Engineered enzymes that Retain and Regenerate their Cofactors Enable Continuous-Flow Biocatalysis
Selected by
Zhang-He Goh
Aqueous synthesis of a small-molecule lanthanide chelator amenable to copper-free click chemistry
Selected by
Zhang-He Goh
Hepatocyte-specific deletion of Pparα promotes NASH in the context of obesity
Selected by
Pablo Ranea Robles
Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification
Selected by
Yasmin Lau
In vivo identification of GTPase interactors by mitochondrial relocalization and proximity biotinylation
Selected by
David Stephens
Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells
Selected by
Mila Basic
A metabolic switch from OXPHOS to glycolysis is essential for cardiomyocyte proliferation in the regenerating heart
Selected by
Andreas van Impel