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Large-scale curvature sensing by epithelial monolayers depends on active cell mechanics and nuclear mechanoadaptation

Marine Luciano, Shi-Lei Xue, Winnok H. De Vos, et al.

A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic

Maria Alimova, Eriene-Heidi Sidhom, Abhigyan Satyam, et al.

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Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses

Willianne Hoepel, Hung-Jen Chen, Sona Allahverdiyeva, et al.

Discussion

Human alveolar Type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells during alveolar repair

Jaymin J. Kathiriya, Chaoqun Wang, Alexis Brumwell, et al.

T cell receptor is required for differentiation but not maintenance of intestinal intraepithelial lymphocytes

Angelina M. Bilate, Mariya London, Tiago B. R. Castro, et al.

Discussion

Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival

Paolo Armando Gagliardi, Maciej Dobrzyński, Marc-Antoine Jacques, et al.

Epithelial Tissues as Active Solids: From Nonlinear Contraction Pulses to Rupture Resistance

Shahaf Armon, Matthew S. Bull, Avraham Moriel, et al.

Discussion

Neural plate targeting by in utero nanoinjection (NEPTUNE) reveals a role for Sptbn2 in neurulation and abdominal wall closure

Katrin Mangold, Jan Mašek, Jingyan He, et al.

Discussion

Brief sensory deprivation triggers cell type-specific structural and functional plasticity in olfactory bulb neurons

Elisa Galliano , Christiane Hahn, Lorcan Browne, et al.

Organoid Easytag: an efficient workflow for gene targeting in human organoids

Dawei Sun, Lewis D. Evans, Emma L. Rawlins

Tissue size controls patterns of cell proliferation and migration in freely-expanding epithelia

Matthew A. Heinrich, Julienne M. LaChance, Tom J. Zajdel, et al.

Discussion

Single-cell longitudinal analysis of SARS-CoV-2 infection in human bronchial epithelial cells

Neal G. Ravindra, Mia Madel Alfajaro, Victor Gasque, et al.

Discussion

The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation

Emma Carley*, Rachel M. Stewart*, Abigail Zieman*, et al.