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Yeast FIT2 homolog is necessary to maintain cellular proteostasis by regulating lipid homeostasis

Peter Shyu, Wei Sheng Yap, Maria L. Gaspar, et al.

Evolutionarily diverse LIM domain-containing proteins bind stressed actin filaments through a conserved mechanism

Jonathan D. Winkelman, Caitlin A. Anderson, Cristian Suarez, et al.

AND

Mechanosensing through direct binding of tensed F-actin by LIM domains

Xiaoyu Sun, Donovan Y. Z. Phua, Lucas Axiotakis Jr., et al.

ER-Mitochondria Contacts Promote Mitochondrial-Derived Compartment Biogenesis

Alyssa M. English, Benoît Kornmann, Janet M. Shaw, et al.

AND

Mitochondrial-Derived Compartments Facilitate Cellular Adaptation to Amino Acid Stress

Max-Hinderk Schuler, Alyssa M. English, Thane J. Campbell, et al.

Discussion

Light microscopy of proteins in their ultrastructural context

Ons M’Saad, Joerg Bewersdorf

Dissecting the nanoscale lipid profile of caveolae

Yong Zhou, Nicholas Ariotti, James Rae, et al.

Discussion

Bariatric surgery reveals a gut-restricted TGR5 agonist that exhibits anti-diabetic effects

Snehal N. Chaudhari, David A. Harris, Hassan Aliakbarian, et al.

Discussion

Oligodendrocyte-derived exosomes promote axonal transport and axonal long-term maintenance

Carsten Frühbeis, Wen Ping Kuo-Elsner, Kerstin Barth, et al.

Ferroptosis contributes to developmental cell death in rice blast

Qing Shen, Meiling Liang, Fan Yang, et al.

ER membranes exhibit phase behavior at sites of organelle contact

Christopher King, Prabuddha Sengupta, Arnold Seo, et al.

Discussion

Tropomyosin Tpm3.1 is required to maintain the structure and function of the axon initial segment

Amr Abouelezz, Holly Stefen, Mikael Segerstråle, et al.

Delineating the rules for structural adaptation of membrane-associated proteins to evolutionary changes in membrane lipidome

Maria Makarova, Maria Peter, Gabor Balogh, et al.

Discussion

A conserved ATG2-GABARAP interaction is critical for phagophore closure

Mihaela Bozic, Luuk van den Bekerom, Beth A. Milne, et al.

Discussion