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FUS Mislocalization Rewires a Cortical Gene Network to Drive 2 Cognitive and Behavioral Impairment in ALS

Raphaelle CASSEL, Félicie LORENC, Aurélie BOMBARDIER, et al.

Discussion

A prophage-encoded anti-phage defense system that prevents phage DNA packaging by targeting the terminase complex

Gil Azulay, Nadejda Sigal, Keren Tzohar Rabinovich, et al.

Discussion

Ancestral sequence reconstruction of the Mic60 Mitofilin domain reveals residues supporting respiration in yeast

Friederike M. C. Benning, Tristan A. Bell, Tran H. Nguyen, et al.

Discussion

Discovery of a Potent and Selective Inhibitor of Human NLRP3 with a Novel Binding Modality and Mechanism of Action

Kevin Wilhelmsen, Aditi Deshpande, Sarah Tronnes, et al.

Discussion

Integrin conformation-dependent neutrophil slowing obstructs the capillaries of the pre-metastatic lung in a model of breast cancer

Frédéric Fercoq, Gemma S. Cairns, Marco De Donatis, et al.

The RNA binding protein HNRNPA2B1 regulates RNA abundance and motor protein activity in neurites

Joelle Lo, Katherine F. Vaeth, Gurprit Bhardwaj, et al.

Significantly reduced, but balanced, rates of mitochondrial fission and fusion are sufficient to maintain the integrity of yeast mitochondrial DNA

Brett T. Wisniewski, Laura L. Lackner

Discussion

TAK1 operates at the primary cilium in non-canonical TGFB/BMP signaling to control heart development

Canan Doganli, Daniel A. Baird, Yeasmeen Ali, et al.

Membrane Curvature Promotes ER-PM Contact Formation via Junctophilin-EHD Interactions

Yang Yang, Luis A. Valencia, Chih-Hao Lu, et al.

A fine kinetic balance of interactions directs transcription factor hubs to genes

Apratim Mukherjee, Samantha Fallacaro, Puttachai Ratchasanmuang, et al.

Modular control of time and space during vertebrate axis segmentation

Ali Seleit, Ian Brettell, Tomas Fitzgerald, et al.

AND

Natural genetic variation quantitatively regulates heart rate and dimension

Jakob Gierten, Bettina Welz, Tomas Fitzgerald, et al.

Notch3 is a genetic modifier of NODAL signalling for patterning asymmetry during mouse heart looping

Tobias Holm Bønnelykke, Marie-Amandine Chabry, Emeline Perthame, et al.

Discussion