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A specialized mRNA translation circuit instated in pluripotency presets the competence for cardiogenesis in humans

Deniz Bartsch, Kaustubh Kalamkar, Gaurav Ahuja, et al.



Selected by Emma Armitage

Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart

Gianluca Amadei, Charlotte E Handford, Joachim De Jonghe, et al.

AND

Mouse-embryo model derived exclusively from embryonic stem cells undergo neurulation and heart development

Kasey Y.C. Lau, Hernan Rubinstein, Carlos W. Gantner, et al.



Selected by Monica Tambalo et al.

A cell fate decision map reveals abundant direct neurogenesis in the human developing neocortex

Laure Coquand, Anne-Sophie Macé, Sarah Farcy, et al.



Selected by Juan Moriano

Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality

Sonia Sabate-Soler, Sarah Louise Nickels, Cláudia Saraiva, et al.



Selected by Emma Wilson

Microstructured hydrogels to guide self-assembly and function of lung alveolospheres

Claudia Loebel, Aaron I. Weiner, Jeremy B. Katzen, et al.



Selected by Julio Sainz de Aja

Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism

Mírian Romitti, Barbara de Faria da Fonsecaa, Gilles Doumont, et al.



Selected by Anna Meier

Self-organized morphogenesis of a human neural tube in vitro by geometric constraints

Eyal Karzbrun, Aimal H. Khankhel, Heitor C. Megale, et al.



Selected by Srivatsava Viswanadha

Multiscale light-sheet organoid imaging framework

Gustavo de Medeiros, Raphael Ortiz, Petr Strnad, et al.



Selected by Osvaldo Contreras

Engineering functional human gastrointestinal organoid tissues using the three primary germ layers separately derived from pluripotent stem cells

Alexandra K. Eicher, Daniel O. Kechele, Nambirajan Sundaram, et al.



Selected by Niveda Udaykumar

Acquisition of alveolar fate and differentiation competence by human fetal lung epithelial progenitor cells

Kyungtae Lim, Walfred Tang, Dawei Sun, et al.



Selected by Rob Hynds

Optogenetic control of apical constriction induces synthetic morphogenesis in mammalian tissues

Guillermo Martínez-Ara, Núria Taberner, Mami Takayama, et al.



Selected by Monica Tambalo

YAP1 Regulates the Self-organized Fate Patterning of hESCs-Derived Gastruloids

Servando Giraldez, Eleonora Stronati, Ling Huang, et al.



Selected by Srivatsava Viswanadha
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