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Human cardiac fibrosis-on-a-chip model recapitulates disease hallmarks and can serve as a platform for drug screening

Olya Mastikhina, Byeong-Ui Moon, Kenneth Williams, et al.

Selected by Hiroyoshi Y. Tanaka

Spontaneous isomerization of long-lived proteins provides a molecular mechanism for the lysosomal failure observed in Alzheimer’s disease

Tyler R. Lambeth, Dylan L. Riggs, Lance E. Talbert, et al.

Selected by Joanna Cross

Transcriptome analysis of Plasmodium berghei during exo-erythrocytic development

Reto Caldelari, Sunil Dogga, Marc W. Schmid, et al.

Selected by Mariana De Niz

Multi-immersion open-top light-sheet microscope for high-throughput imaging of cleared tissues

Adam K. Glaser, Nicholas P. Reder, Ye Chen, et al.

Selected by Tim Fessenden

Stable knockout and complementation of receptor expression using in vitro cell line derived reticulocytes for dissection of host malaria invasion requirements

Timothy J Satchwell, Katherine E Wright, Katy L Haydn-Smith, et al.

Selected by Alyson Smith

Biofilm/Persister/Stationary Phase Bacteria Cause More Severe Disease Than Log Phase Bacteria II Infection with Persister Forms of Staphylococcus aureus Causes a Chronic Persistent Skin Infection with More Severe Lesion that Takes Longer to Heal and is not Eradicated by the Current Recommended Treatment in Mice

Rebecca Yee, Yuting Yuan, Cory Brayton, et al.

Selected by Snehal Kadam

Psychiatric risk gene NT5C2 regulates protein translation in human neural progenitor cells

Rodrigo R.R. Duarte, Nathaniel D. Bachtel, Marie-Caroline Cotel, et al.

Selected by Joanna Cross

Transient intracellular acidification regulates the core transcriptional heat shock response

Catherine G Triandafillou, Christopher D Katanski, Aaron R Dinner, et al.

Selected by Srivats Venkataramanan

OptoGranules reveal the evolution of stress granules to ALS-FTD pathology

Peipei Zhang, Baochang Fan, Peiguo Yang, et al.

Selected by Srivats Venkataramanan

SWI/SNF remains localized to chromatin in the presence of SCHLAP1

Jesse R Raab, Keriayn N Smith, Camarie C Spear, et al.

Selected by Carmen Adriaens

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