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The chromatin, topological and regulatory properties of pluripotency-associated poised enhancers are conserved in vivo

Giuliano Crispatzu, Rizwan Rehimi, Tomas Pachano, et al.



Selected by Sergio Menchero

1

Orphan CpG islands boost the regulatory activity of poised enhancers and dictate the responsiveness of their target genes

Tomás Pachano, Víctor Sánchez-Gaya, María Mariner-Faulí, et al.



Selected by Jesus Victorino

1

The deubiquitinase Usp9x regulates PRC2-mediated chromatin reprogramming during mouse development

Trisha A. Macrae, Miguel Ramalho-Santos



Selected by Sergio Menchero

1

Sexually Dimorphic DNA Damage Responses and Mutation Avoidance in the Mouse Germline

Jordana C. Bloom, John C. Schimenti



Selected by Jennifer Ann Black

2

Primate naïve pluripotent stem cells stall in the G1 phase of the cell cycle and differentiate prematurely during embryo colonization

Irène Aksoy, Cloé Rognard, Anaïs Moulin, et al.



Selected by Pierre Osteil

1

Live-cell 3D single-molecule tracking reveals how NuRD modulates enhancer dynamics

S Basu, O Shukron, A Ponjavic, et al.

AND

Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy

Miles K. Huseyin, Robert J. Klose



Selected by Gabriel Aughey

2

Transcriptional control of apical protein clustering drives de novo cell polarity establishment in the early mouse embryo

Meng Zhu, Peizhe Wang, Charlotte E. Handford, et al.



Selected by Aswini Babu

1

Trophectoderm Potency is Retained Exclusively in Human Naïve Cells

Ge Guo, Giuliano Giuseppe Stirparo, Stanley Strawbridge, et al.



Selected by Sergio Menchero

1

Membrane tension mediated mechanotransduction drives fate choice in embryonic stem cells

Henry De Belly, Philip H. Jones, Ewa K. Paluch, et al.

AND

Cell surface mechanics gate stem cell differentiation

Martin Bergert, Sergio Lembo, Danica Milovanović, et al.



Selected by Joseph Jose Thottacherry

1

Differential regulation of lineage commitment in human and mouse primed pluripotent stem cells by NuRD

Ramy Ragheb, Sarah Gharbi, Julie Cramard, et al.



Selected by Gabriel Aughey

1

DRP1-mediated regulation of mitochondrial dynamics determines the apoptotic response upon embryonic differentiation

Barbara Pernaute, Juan Miguel Sánchez Nieto, Salvador Pérez-Montero, et al.



Selected by Katarzyna Kuzmicz-Kowalska

1

Differences in mitochondrial activity trigger cell competition during early mouse development

Ana Lima, Gabriele Lubatti, Jörg Burgstaller, et al.



Selected by Teresa Rayon

1

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