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Microglia become hypofunctional and release metalloproteases and tau seeds after phagocytosing live neurons with P301S tau aggregates

Jack H. Brelstaff, Matthew Mason, Taxiarchis Katsinelos, et al.

Selected by 11 March 2021

Kristina Kuhbandner

Neuroscience

Bromodomain Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV2 Infection in Pre-Clinical Models

Richard J Mills, Sean J Humphrey, Patrick RJ Fortuna, et al.

Selected by 27 November 2020

Alexander Ward, Osvaldo Contreras

Bioengineering

Functional diversification of Ser-Arg rich protein kinases to control ubiquitin-dependent neurodevelopmental signalling

Francisco Bustos, Anna Segarra-Fas, Gino Nardocci, et al.

Selected by 22 September 2020

Sree Rama Chaitanya

Developmental Biology

Small molecules exploiting structural differences within microRNA-200 precursors family members reverse a type 2 diabetes phenotype

Hafeez S. Haniff, Xiaohui Liu, Laurent Knerr, et al.

Selected by 25 August 2020

Zhang-He Goh

Pharmacology and Toxicology

A Transcriptional Switch Governing Fibroblast Plasticity Underlies Reversibility of Chronic Heart Disease

Michael Alexanian, Pawel F. Przytycki, Rudi Micheletti, et al.

Selected by 11 August 2020

Osvaldo Contreras, Alexander Ward

Cell Biology

Conservation of the Toxoplasma conoid proteome in Plasmodium reveals a cryptic conoid feature that differentiates between blood- and vector-stage zoites

Ludek Koreny, Mohammad Zeeshan, Konstantin Barylyuk, et al.

Selected by 23 July 2020

Mariana De Niz

Cell Biology

Expansion Microscopy provides new insights into the cytoskeleton of malaria parasites including the conservation of a conoid

Eloïse Bertiaux, Aurélia C Balestra, Lorène Bournonville, et al.

Selected by 19 July 2020

Mariana De Niz

Cell Biology

Characterization of the Novel Mitochondrial Genome Segregation Factor TAP110 in Trypanosoma brucei

Simona Amodeo, Ana Kalichava, Albert Fradera-Sola, et al.

Selected by 02 July 2020

Jennifer Ann Black

Molecular Biology

Replication protein A binds RNA and promotes R-loop formation

Olga M. Mazina, Srinivas Somarowthu, Lyudmila Y. Kadyrova, et al.

Selected by 22 June 2020

Giuseppina D'Alessandro

Molecular Biology

A subcellular atlas of Toxoplasma reveals the functional context of the proteome

Konstantin Barylyuk, Ludek Koreny, Huiling Ke, et al.

Selected by 16 June 2020

Mariana De Niz

Cell Biology

L-bodies are novel RNA-protein condensates driving RNA transport in Xenopus oocytes

Christopher R. Neil, Samantha P. Jeschonek, Sarah E. Cabral, et al.

Selected by 28 May 2020

Maiko Kitaoka

Cell Biology

Interspecies differences in proteome turnover kinetics are correlated with lifespans and energetic demands

Kyle Swovick, Denis Firsanov, Kevin A. Welle, et al.

Selected by 18 May 2020

Teresa Rayon

Evolutionary Biology