Search results

CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity

Madison B. Adolph, Atharv S. Garje, Swati Balakrishnan, et al.

Selected by 06 September 2023

Jessica Chevallier, Pierre Caron

Discussion

A transposase-derived gene required for human brain development

Luz Jubierre Zapater, Elias Rodriguez-Fos, Merce Planas-Felix, et al.

Selected by 06 July 2023

Amanda Ivanoff

Nociceptor neuroimmune interactomes reveal cell type- and injury-specific inflammatory pain pathways

Aakanksha Jain, Benjamin M. Gyori, Sara Hakim, et al.

Selected by 05 July 2023

Patrick Penndorf

Caveola mechanotransduction reinforces the cortical cytoskeleton to promote epithelial resilience

John W. Brooks, Vikas Tillu, Suzie Verma, et al.

Selected by 15 June 2023

Teodora Piskova

Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis

Camille Gelot, Marton Tibor Kovacs, Simona Miron, et al.

Selected by 05 June 2023

Pierre Caron

Discussion

EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells

B. van de Kooij, A. Schreuder, R.S. Pavani, et al.

Selected by 15 May 2023

Jennifer Ann Black

Therapeutic strategy for spinal muscular atrophy by combining gene supplementation and genome editing

Fumiyuki Hatanaka, Keiichiro Suzuki, Kensaku Shojima, et al.

Selected by 03 May 2023

Preethi Krishnaraj

Discussion

Actin nucleators safeguard replication forks by limiting nascent strand degradation

Jadwiga Nieminuszczy, Peter R. Martin, Ronan Broderick, et al.

Selected by 22 March 2023

Roberto Amadio

Discussion

BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote replication fork stability and continuous DNA synthesis

Daniel Salas-Lloret, Néstor García-Rodríguez, Lisanne Giebel, et al.

Selected by 09 March 2023

Pierre Caron

Single-strand mismatch and damage patterns revealed by single-molecule DNA sequencing

Mei Hong Liu, Benjamin Costa, Una Choi, et al.

Selected by 28 February 2023

Kerryn Elliott

Discussion

Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment

Julia Kolb, Nora John, Kyoohyun Kim, et al.

Selected by 22 February 2023

Laura Celotto

Alumni

Phosphoproteomics of cellular mechanosensing reveals NFATC4 as a regulator of myofibroblast activity

Laura F. Mattner, Zhen Zeng, Christoph H. Mayr, et al.

Selected by 21 February 2023

Rob Hynds