Preprint highlights, selected by the biological community
A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic
AND
Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses
Selected by
31 July 2020
Yen-Chung Chen
Severe immunodeficiency in mice lacking DNA repair factors XLF and Mri
Selected by
27 July 2020
Jennifer Ann Black
Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen
AND
Tamoxifen reduces inflammatory infiltration of neutrophils in the airways
Selected by
25 July 2020
Zhang-He Goh, Josie Gibson
The small RNA ErsA plays a role in the regulatory network of Pseudomonas aeruginosa pathogenicity in airways infection
Selected by
25 July 2020
Zhang-He Goh
T cell receptor is required for differentiation but not maintenance of intestinal intraepithelial lymphocytes
Selected by
20 July 2020
Pedro Papotto
BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity
Selected by
14 July 2020
Louise Fraser