Search results

CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis

Avi J. Samelson, Nabeela Ariqat, Justin McKetney, et al.

Selected by Kritika Mehta

Conserved cardiolipin-mitochondrial ADP/ATP carrier interactions assume distinct structural and functional roles that are clinically relevant

Nanami Senoo, Dinesh K. Chinthapalli, Matthew G. Baile, et al.

Selected by Barbora Knotkova

Coordinated regulation of photosynthesis and translation via NIK1/RPL10/LIMYB signaling module in response to biotic and abiotic stresses

Ruan M. Teixeira, Marco Aurélio Ferreira, Otávio J.B. Brustolini, et al.

Selected by Yueh Cho

Sucrose overconsumption impairs feeding circuit dynamics and promotes palatable food intake

Carolyn M. Lorch, Nikolas W. Hayes, Jessica L. Xia, et al.

Selected by Cláudia Gil

Coxiella burnetii actively blocks IL-17-induced oxidative stress in macrophages

Tatiana M. Clemente, Leonardo Augusto, Rajendra K. Angara, et al.

Selected by UofA IMB565

A Single Laccase Acts as a Key Component of Environmental Sensing in a Broad Host Range Fungal pathogen

Nathaniel M. Westrick, Eddie G. Dominguez, Christina M. Hull, et al.

Selected by UofA IMB565

Inhibition of Cellular MEK/ERK Signaling Suppresses Murine Papillomavirus Type 1 Replicative Activities and Promotes Tumor Regression

Adrian J. Luna, Jesse M. Young, Rosa T. Sterk, et al.

Selected by Yvonne Xinyi Lim

SQ3370, the first clinical click chemistry-activated cancer therapeutic, shows safety in humans and translatability across species

Sangeetha Srinivasan, Nathan A. Yee, Michael Zakharian, et al.

Selected by Zhang-He Goh

Inhibition of Centrosome Clustering Reduces Cystogenesis and Improves Kidney Function in Autosomal Dominant Polycystic Kidney Disease

Tao Cheng, Aruljothi Mariappan, Ewa Langner, et al.

Selected by Fiona Macleod

Humoral and T-cell-mediated responses to a pre-clinical Zika vaccine candidate that utilizes a unique insect-specific flavivirus platform

Danielle L. Porier, Awadalkareem Adam, Lin Kang, et al.

Selected by Lucy Bowden

3D genome organization around nuclear speckles drives mRNA splicing efficiency

Prashant Bhat, Amy Chow, Benjamin Emert, et al.

Selected by Diego Martínez

Sex-determining 3D regulatory hubs revealed by genome spatial auto-correlation analysis

Irene Mota-Gómez, Juan Antonio Rodríguez, Shannon Dupont, et al.

Selected by Martin Estermann