I am currently a postdoctoral researcher at The University of Sheffield. I completed my PhD, at both The University of Sheffield and A*Star labs in Singapore, where I examined the role of host cell autophagy in the control of intracellular pathogens using cellular level imaging. I am interested in understanding host-pathogen interactions, specifically how pathogens evade host immune defences to cause infection, and how the dynamics of infection change over time. I am also interested in microscopy, autophagy, immune cells and antimicrobial resistance.
An arginase 2 promoter transgenic illuminates anti-inflammatory signalling in zebrafish
Dram1 confers resistance to Salmonella infection
Gut microbiome features are associated with sepsis onset and outcomes
Intestinal infection results in impaired lung innate immunity to secondary respiratory infection
Amoeba predation of Cryptococcus neoformans results in pleiotropic changes to traits associated with virulence
Galectin-8 senses phagosomal damage and recruits selective autophagy adapter TAX1BP1 to control Mycobacterium tuberculosis infection in macrophages
Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen
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Tamoxifen reduces inflammatory infiltration of neutrophils in the airways
Trophic cooperation promotes bacterial survival of Staphylococcus aureus and Pseudomonas aeruginosa
Phage infection mediates inhibition of bystander bacteria
Dissecting individual pathogen-commensal interactions within a complex gut microbiota community
