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I am currently in my first position as a postdoctoral researcher at The University of Sheffield. I completed my PhD, at both The University of Sheffield and at A*Star labs in Singapore, which focused on using cellular level imaging to understand the role of host cell autophagy in the control of intracellular pathogens. I am interested in understanding host-pathogen interactions in infection, specifically how pathogens can start the initial infection, and how the dynamics of infection change over time. My current research includes both fungal and bacterial pathogens, and how they are able to evade host immune defences to cause infection. I am mainly focussed on microbiology, but my other key interests are microscopy, autophagy, immune cells and antimicrobial resistance.
Gut microbiome features are associated with sepsis onset and outcomes
| Selected by | Josie Gibson |
Intestinal infection results in impaired lung innate immunity to secondary respiratory infection
| Selected by | Josie Gibson |
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Amoeba predation of Cryptococcus neoformans results in pleiotropic changes to traits associated with virulence
| Selected by | Josie Gibson |
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Galectin-8 senses phagosomal damage and recruits selective autophagy adapter TAX1BP1 to control Mycobacterium tuberculosis infection in macrophages
| Selected by | Josie Gibson, Zhang-He Goh |
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Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen
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Tamoxifen reduces inflammatory infiltration of neutrophils in the airways
| Selected by | Zhang-He Goh, Josie Gibson |
Trophic cooperation promotes bacterial survival of Staphylococcus aureus and Pseudomonas aeruginosa
| Selected by | Josie Gibson |
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Phage infection mediates inhibition of bystander bacteria
| Selected by | Josie Gibson |
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Dissecting individual pathogen-commensal interactions within a complex gut microbiota community
| Selected by | Josie Gibson |
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