Close

Zhang-He Goh

University of Cambridge, Agency for Science, Technology and Research (A*STAR) Singapore, University of Cambridge

I am a Pharmacy graduate from the National University of Singapore (NUS) with a research interest in organic synthesis, toxicology, and infectious diseases. In October 2020, I will be joining the University of Cambridge’s Syntech CDT to embark on my doctoral studies in Chemistry.

I have been affiliated with the Agency for Science, Technology, and Research (A*STAR) since 2011, and have worked in the following Research Institutes (RIs):

In NUS, my undergraduate research work consisted of two research projects that revolved around tuberculosis: 1) discovering antitubercular agents that utilise new mechanisms of action against Mycobacterium tuberculosis, and 2) finding ways to reduce side effects of the tuberculosis drug regimens in use.

Zhang-He Goh has added 42 preLight posts

Discovery and visualization of uncharacterized drug-protein adducts using mass spectrometry

Michael Riffle, Michael R. Hoopmann, Daniel Jaschob, et al.



Selected by Zhang-He Goh

The Design, Synthesis, and Evaluation of Hypoxia-Activated Prodrugs of the KDAC Inhibitor Panobinostat

Ewen Calder, Anna Skwarska, Deborah Sneddon, et al.



Selected by Zhang-He Goh

Design of smart antibody mimetics with photosensitive switches

Lian He, Peng Tan, Yun Huang, et al.



Selected by Zhang-He Goh

Accelerated erythrocyte senescence causes dose-limiting anemia of antimalarial enolase inhibitors

Andrew J. Jezewski, Yu-Hsi Lin, Julie A. Reisz, et al.



Selected by Zhang-He Goh

Systematic Engineering of Artificial Metalloenzymes for New-to-Nature Reactions

Tobias Vornholt, Fadri Christoffel, Michela M. Pellizzoni, et al.



Selected by Zhang-He Goh

Antifungal effects of PC945, a novel inhaled triazole, on Candida albicans-infected immunocompromised mice

Yuki Nishimoto, Kazuhiro Ito, Genki Kimura, et al.



Selected by Zhang-He Goh

Pharmacological Insights into Safety and Efficacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of Heart Failure

Patricia Rueda, Jon Merlin, Stefano Chimenti, et al.



Selected by Zhang-He Goh

Small molecules exploiting structural differences within microRNA-200 precursors family members reverse a type 2 diabetes phenotype

Hafeez S. Haniff, Xiaohui Liu, Laurent Knerr, et al.



Selected by Zhang-He Goh

Toll-like receptor 4 is activated by platinum and contributes to cisplatin-induced ototoxicity

Ghazal Babolmorad, Asna Latif, Niall M. Pollock, et al.

AND

Application of the in vivo oxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity

Francisco Inesta-Vaquera, Panida Navasumrit, Colin J. Henderson, et al.



Selected by Zhang-He Goh

Electron Transfer from Cytochrome P450 Reductase to Cytochrome P450: Towards a Structural and Dynamic Understanding

Goutam Mukherjee, Prajwal P. Nandekar, Rebecca C. Wade



Selected by Zhang-He Goh

Galectin-8 senses phagosomal damage and recruits selective autophagy adapter TAX1BP1 to control Mycobacterium tuberculosis infection in macrophages

Samantha L. Bell, Kayla L. Lopez, Jeffery S. Cox, et al.



Selected by Josie Gibson, Zhang-He Goh

1

Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen

Aravind Madhavan, K B Arun, Akhil Raj Pushparajan, et al.

AND

Tamoxifen reduces inflammatory infiltration of neutrophils in the airways

Agustín Mansilla, Jaime Soto, Claudio Henríquez, et al.



Selected by Zhang-He Goh, Josie Gibson

Sign up to customise the site to your preferences and to receive alerts

Register here
Close