I am a scientist at the Agency for Science, Technology, and Research (A*STAR), and currently work at the Institute Of Sustainability for Chemicals, Energy And Environment (ISCE2).
I completed my PhD in Chemistry at the University of Cambridge in 2025. Before that, I was a Pharmacy graduate from the National University of Singapore (NUS) (2019).
My first foray into research was in 2011 as a young scientist at the Institute of Materials Research and Engineering (IMRE). Since then, I have worked in the following Research Entities (REs):
- Experimental Drug Development Centre (EDDC) (2019 – 2020)
- Bioinformatics Institute (BII) (2017)
- Institute of Bioengineering and Nanotechnology (2015)
My graduate research revolved around developing hypervalent iodine reagents for protein functionalisation. Before that, my undergraduate research work consisted of two research projects that revolved around tuberculosis: 1) discovering antitubercular agents that utilise new mechanisms of action against Mycobacterium tuberculosis, and 2) finding ways to reduce side effects of the tuberculosis drug regimens in use.
Ribosome rescue inhibitors clear Neisseria gonorrhoeae in vivo using a new mechanism
Zhang-He Goh
A therapeutic combination of two small molecule toxin inhibitors provides pancontinental preclinical efficacy against viper snakebite
Zhang-He Goh
Broad-spectrum antivirals of protoporphyrins inhibit the entry of highly pathogenic emerging viruses
Zhang-He Goh
The antimicrobial peptide DGL13K is active against resistant gram-negative bacteria and subinhibitory concentrations stimulate bacterial growth without causing resistance
Zhang-He Goh
A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues
Zhang-He Goh
Orally Bioavailable Endochin-like Quinolone Carbonate Ester Prodrug Reduces Toxoplasma gondii Brain Cysts
Zhang-He Goh
Patient-derived ovarian cancer organoids mimic clinical response and exhibit heterogeneous inter- and intrapatient drug responses
Zhang-He Goh
Effective buprenorphine use and tapering strategies: Endorsements and insights by people in recovery from opioid use disorder on a Reddit forum
Zhang-He Goh
Combining antibiotics with antivirulence compounds is effective and can reverse selection for antibiotic resistance in Pseudomonas aeruginosa
Zhang-He Goh
COMET: A toolkit for composing customizable genetic programs in mammalian cells
Zhang-He Goh
Engineering Phage Host-Range and Suppressing Bacterial Resistance Through Phage Tail Fiber Mutagenesis
Zhang-He Goh
On-demand, cell-free biomanufacturing of conjugate vaccines at the point-of-care
Zhang-He Goh







2 years
Zhang-He Goh
Thank you for pointing this out! I have now edited the Figure accordingly.