Close

Toxicology of toxicants, existing therapeutics, and investigational drugs

Preprints that describe the toxicology of environmental pollutants and existing and upcoming drugs. Includes both toxicokinetics and toxicodynamics, as well as technological improvements that will help in the characterisation of this field.

List by Zhang-He Goh

Preprints:

Are Zinc oxide nanoparticles safe? A structural study on human serum albumin using in vitro and in silico methods

Marziyeh Hassanian, Hassan Aryapour, Alireza Goudarzi, Masoud Bezi Javan

https://www.biorxiv.org/content/10.1101/503797v2

Zinc Oxide (ZnO) nanoparticles are heavily used in various biomedical and formulation applications. In their preprint, Hassanian et al. investigate the toxicity of ZnO nanoparticles, using in vitro and in silico studies to understand the effects that ZnO nanoparticles have on human serum albumin (HSA).

A Bile Duct-on-a-Chip with Organ-Level Functions

Yu Du, Gauri Khandekar, Jessica Llewellyn, William Polacheck, Christopher S. Chen, Rebecca G. Wells

https://www.biorxiv.org/content/10.1101/594291v1

The bile duct-on-a-chip invention by Du et al. could be used to further explore the hepatobiliary tree, investigate pharmacokinetic testing phases of drug discovery, and understand the hepatobiliary system more holistically. Taken together, these would aid in efforts to characterise how drugs and toxins might affect the entire hepatobiliary system.

Categories: pharmacology and toxicology

 

Posted on: 5 June 2019

(No Ratings Yet)

Have your say

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Sign up to customise the site to your preferences and to receive alerts

Register here

Also in the pharmacology and toxicology category:

FENS 2020

A collection of preprints presented during the virtual meeting of the Federation of European Neuroscience Societies (FENS) in 2020

 



List by Ana Dorrego-Rivas

COVID-19 / SARS-CoV-2 preprints

List of important preprints dealing with the ongoing coronavirus outbreak. See http://covidpreprints.com for additional resources and timeline, and https://connect.biorxiv.org/relate/content/181 for full list of bioRxiv and medRxiv preprints on this topic

 



List by Dey Lab, Zhang-He Goh

1

Drug use in special populations

Any drugs that are being used in special populations: Patients with liver and kidney failure, in paediatrics, in geriatrics, and in pregnant or lactating patients. Includes the discovery of factors that could potentially affect drug use in these special populations.

 



List by Zhang-He Goh

Antimicrobials: Discovery, clinical use, and development of resistance

Preprints that describe the discovery of new antimicrobials and any improvements made regarding their clinical use. Includes preprints that detail the factors affecting antimicrobial selection and the development of antimicrobial resistance.

 



List by Zhang-He Goh

Anticancer agents: Discovery and clinical use

Preprints that describe the discovery of anticancer agents and their clinical use. Includes both small molecules and macromolecules like biologics.

 



List by Zhang-He Goh

Advances in Drug Delivery

Advances in formulation technology or targeted delivery methods that describe or develop the distribution of small molecules or large macromolecules to specific parts of the body.

 



List by Zhang-He Goh

Also in the pharmacology and toxicology category:

G6b-B antibody-based cis-acting platelet receptor inhibitors (CAPRIs) as a new family of anti-thrombotic therapeutics

Alexandra Mazharian, Ophélie Bertin, Amrita Sarkar, et al.

Selected by 03 June 2024

Simon Cleary

Pharmacology and Toxicology

Pervasive sublethal effects of agrochemicals as contributing factors to insect decline

Lautaro Gandara, Richard Jacoby, François Laurent, et al.

Selected by 07 February 2024

Roberto Amadio

Animal Behavior and Cognition

Mixed Alkyl/Aryl Phosphonates Identify Metabolic Serine Hydrolases as Antimalarial Targets

John M. Bennett, Sunil K. Narwal, Stephanie Kabeche, et al.

Selected by 02 February 2024

Zhang-He Goh

Microbiology
Close