I’m a Postdoctoral Scientist working on cell-based strategies for improving our understanding of skeletal muscle regeneration and heart repair under the supervision of Dr Richard Harvey at The Victor Chang Cardiac Research Institute, Sydney, Australia.
I started my scientific journey as an undergraduate researcher in Dr Juan Larrain’s Lab studying the developmental role of the Wnt/PCP pathway in neural tube closure. Then, I completed my PhD studying tissue-resident fibro-adipogenic progenitors (FAPs) biology, plasticity, and their role in muscle and heart regeneration/repair in Dr Enrique Brandan’s Lab with the co-supervision of Dr Fabio Rossi at the University of British Columbia in 2019. I’ve been focused on comprehending muscular dystrophies and fibrosis. Last but not least, I’m also interested in myogenic fate determination and differentiation.
Multiscale light-sheet organoid imaging framework
Osvaldo Contreras
Coronary blood vessels from distinct origins converge to equivalent states during mouse and human development
Yen Tran, Osvaldo Contreras
Bromodomain Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV2 Infection in Pre-Clinical Models
Alexander Ward, Osvaldo Contreras
Human skeletal muscle CD90+ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients
Osvaldo Contreras, Nicolas Collao
A Transcriptional Switch Governing Fibroblast Plasticity Underlies Reversibility of Chronic Heart Disease
Osvaldo Contreras, Alexander Ward