Prenatal inflammation reprograms hyperactive ILC2s that promote allergic lung inflammation and airway dysfunction
Selected by
Marina Schernthanner
A Window into Mammalian Basement Membrane Development: Insights from the mTurq2-Col4a1 Mouse Model
Selected by
Uwe Töpfer
NAD+ metabolism is a key modulator of bacterial respiratory epithelial infections
Selected by
Matheus Atella de Oliveira, Marcus Oliveira
Caveola mechanotransduction reinforces the cortical cytoskeleton to promote epithelial resilience
Selected by
Teodora Piskova
Pseudomonas aeruginosa contracts mucus to rapidly form biofilms in tissue-engineered human airways
Selected by
Snehal Kadam
Three-axis classification of mouse lung mesenchymal cells reveals two populations of myofibroblasts
Selected by
Sagar Varankar
Acquisition of alveolar fate and differentiation competence by human fetal lung epithelial progenitor cells
Selected by
Rob Hynds
Inflammatory blockade prevents injury to the developing pulmonary gas exchange surface in preterm primates
Selected by
Sagar Varankar
Collagen polarization provides a structural memory for the elongation of epithelial anlage
Selected by
Ilaria Di Meglio
A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic
AND
Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses
Selected by
Yen-Chung Chen
Galectin-8 senses phagosomal damage and recruits selective autophagy adapter TAX1BP1 to control Mycobacterium tuberculosis infection in macrophages
Selected by
Josie Gibson, Zhang-He Goh
Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen
AND
Tamoxifen reduces inflammatory infiltration of neutrophils in the airways
Selected by
Zhang-He Goh, Josie Gibson