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Amyotrophic lateral sclerosis associated mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex

MS Dyer, KE Lewis, AK Walker, et al.

Upregulation and cell specificity of C₄ genes are derived from ancestral C₃ gene regulatory networks

Pallavi Singh, Sean R. Stevenson, Ivan Reyna-Llorens, et al.

Discussion

The First Mitotic Division of the Human Embryo is Highly Error-prone

Emma Ford, Cerys E. Currie, Deborah M. Taylor, et al.

Discussion

Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen

Aravind Madhavan, K B Arun, Akhil Raj Pushparajan, et al.

AND

Tamoxifen reduces inflammatory infiltration of neutrophils in the airways

Agustín Mansilla, Jaime Soto, Claudio Henríquez, et al.

Discussion

The small RNA ErsA plays a role in the regulatory network of Pseudomonas aeruginosa pathogenicity in airways infection

Silvia Ferrara, Alice Rossi, Serena Ranucci, et al.

Discussion

RefPlantNLR: a comprehensive collection of experimentally validated plant NLRs

Jiorgos Kourelis, Sophien Kamoun

Surface area-to-volume ratio, not cellular rigidity, determines red blood cell traversal through small capillaries

Arman Namvar, Adam J. Blanch, Matthew W. Dixon, et al.

Cardioids reveal self-organizing principles of human cardiogenesis

Pablo Hofbauer, Stefan Jahnel, Nora Papai, et al.

A systematic examination of preprint platforms for use in the medical and biomedical sciences setting

Jamie J Kirkham, Naomi Penfold, Fiona Murphy, et al.

An open-source experimental framework for automation of cell biology experiments

Pavel Katunin, Ashley Cadby, Anton Nikolaev

A lung-on-chip model reveals an essential role for alveolar epithelial cells in controlling bacterial growth during early tuberculosis

Vivek V. Thacker, Neeraj Dhar, Kunal Sharma, et al.

Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival

Paolo Armando Gagliardi, Maciej Dobrzyński, Marc-Antoine Jacques, et al.