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An early cell shape transition drives evolutionary expansion of the human forebrain

Silvia Benito-Kwiecinski, Stefano L. Giandomenico, Magdalena Sutcliffe, et al.

Selected by 31 July 2020

Monica Tambalo et al.

Evolutionary Biology

A flagellate-to-amoeboid switch in the closest living relatives of animals

Thibaut Brunet, Marvin Albert, William Roman, et al.

Selected by 30 July 2020

Ankita Jha

Evolutionary Biology

Upregulation and cell specificity of C4 genes are derived from ancestral C3 gene regulatory networks

Pallavi Singh, Sean R. Stevenson, Ivan Reyna-Llorens, et al.

Selected by 30 July 2020

Ying Sun

Plant Biology

Increased SGK1 activity potentiates mineralocorticoid/NaCl-induced hypertension and kidney injury

Catalina Sierra-Ramos, Silvia Velazquez-Garcia, Ayse G. Keskus, et al.

Selected by 29 July 2020

Nándor Lipták

Genetics

The First Mitotic Division of the Human Embryo is Highly Error-prone

Emma Ford, Cerys E. Currie, Deborah M. Taylor, et al.

Selected by 28 July 2020

Grace Lim

Cell Biology

Electron Transfer from Cytochrome P450 Reductase to Cytochrome P450: Towards a Structural and Dynamic Understanding

Goutam Mukherjee, Prajwal P. Nandekar, Rebecca C. Wade

Selected by 27 July 2020

Zhang-He Goh

Pharmacology and Toxicology

Severe immunodeficiency in mice lacking DNA repair factors XLF and Mri

Sergio Castañeda-Zegarra, Qindong Zhang, Amin Alirezaylavasani, et al.

Selected by 27 July 2020

Jennifer Ann Black

Immunology

CTCF Mediates Dosage and Sequence-context-dependent Transcriptional Insulation through Formation of Local Chromatin Domains

Hui Huang, Quan Zhu, Adam Jussila, et al.

Selected by 25 July 2020

Clarice Hong

Genetics

Galectin-8 senses phagosomal damage and recruits selective autophagy adapter TAX1BP1 to control Mycobacterium tuberculosis infection in macrophages

Samantha L. Bell, Kayla L. Lopez, Jeffery S. Cox, et al.

Selected by 25 July 2020

Josie Gibson, Zhang-He Goh

Microbiology

Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen

Aravind Madhavan, K B Arun, Akhil Raj Pushparajan, et al.

AND

Tamoxifen reduces inflammatory infiltration of neutrophils in the airways

Agustín Mansilla, Jaime Soto, Claudio Henríquez, et al.

Selected by 25 July 2020

Zhang-He Goh, Josie Gibson

Pharmacology and Toxicology

The small RNA ErsA plays a role in the regulatory network of Pseudomonas aeruginosa pathogenicity in airways infection

Silvia Ferrara, Alice Rossi, Serena Ranucci, et al.

Selected by 25 July 2020

Zhang-He Goh

Pharmacology and Toxicology

Human alveolar Type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells during alveolar repair

Jaymin J. Kathiriya, Chaoqun Wang, Alexis Brumwell, et al.

Selected by 24 July 2020

Julio Sainz de Aja

Cell Biology