Search results

CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis

Avi J. Samelson, Nabeela Ariqat, Justin McKetney, et al.

Selected by 21 July 2023

Kritika Mehta

Discussion

An intestinal sphingolipid promotes neuronal health across generations

Wenyue Wang, Tessa Sherry, Xinran Cheng, et al.

Selected by 29 August 2022

Chee Kiang Ewe

Real-time visualization of mRNA synthesis during memory formation in live animals

Byung Hun Lee, Jae Youn Shim, Hyungseok C. Moon, et al.

Selected by 27 October 2021

Kristina Kuhbandner et al.

Ageing-associated myelin dysfunction drives amyloid deposition in mouse models of Alzheimer’s disease

Constanze Depp, Ting Sun, Andrew Octavian Sasmita, et al.

Selected by 19 August 2021

Kristina Kuhbandner

Tau assemblies enter the cytosol of neurons in a cholesterol sensitive manner

Benjamin J. Tuck, Taxiarchis Katsinelos, Lauren V. C. Miller, et al.

Selected by 07 July 2021

Emma Wilson

Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating other proteins aggregation

Urszula Nowicka, Piotr Chroscicki, Karen Stroobants, et al.

Selected by 20 May 2021

Eric McGregor

Discussion

Microglia become hypofunctional and release metalloproteases and tau seeds after phagocytosing live neurons with P301S tau aggregates

Jack H. Brelstaff, Matthew Mason, Taxiarchis Katsinelos, et al.

Selected by 11 March 2021

Kristina Kuhbandner

Discussion

Structure of an infectious mammalian prion

Allison Kraus, Forrest Hoyt, Cindi L. Schwartz, et al.

Selected by 04 March 2021

Jennifer Ann Black

Neuronal Enhancers are Hotspots For DNA Single-Strand Break Repair

Wei Wu, Sarah E. Hill, William J. Nathan, et al.

Selected by 06 January 2021

Giuseppina D'Alessandro, Sree Rama Chaitanya

Discussion

Functional diversification of Ser-Arg rich protein kinases to control ubiquitin-dependent neurodevelopmental signalling

Francisco Bustos, Anna Segarra-Fas, Gino Nardocci, et al.

Selected by 22 September 2020

Sree Rama Chaitanya

Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis

Ruilin Tian, Anthony Abarientos, Jason Hong, et al.

Selected by 24 August 2020

Berrak Ugur

CSPα reduces aggregates and rescues striatal dopamine release in αsynuclein transgenic mice

L Caló, E Hidari, M Wegrzynowicz, et al.

Selected by 21 August 2020

Kristina Kuhbandner