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Microglia extract neuronal proteolytic organelles via skoupocytosis

Renee Pepper, Jacqueline M. Griswold, Frances Middleton-Davis, et al.

MechanoMaST – a multimodal pipeline for spatially registering mechanical and transcriptomic tissue data

Linda Decker, Dmitrii Olisov, Nikolai Schleußner, et al.

AND

Paired-surface spatial mechanomics links tissue stiffness maps to spatial transcriptomics

Huan Ting Ong, Yuting Lou, Jake Turley, et al.

SPOTTER: Automated Tissue-Barcoding Platform for Spatial proteomics and Phosphoproteomics

Yuanwei Xu, Hyeon-Cheol Park, Jason Li, et al.

Profilin 1 maintains cell cycle fidelity to prevent unscheduled genome doubling and polyploidy in cancer

Federica Scotto di Carlo, Sharon Russo, Simon Gemble, et al.

Discussion

A pre-rRNA positive feedback loop drives malignant ribosome biogenesis

Emilie L. Alard, Martin Dodel, Shannon N. Russell, et al.

Targeting CXADR-mediated AKT signaling suppresses tumorigenesis and enhances chemotherapy efficacy in Ewing sarcoma

Alina Ritter, Malenka Zimmermann, Florian H. Geyer, et al.

Discussion

4,5-dihydroxyhexanoic acid is a robust circulating and urine marker of mitochondrial disease and its severity

Owen S. Skinner, Maria Miranda, Fangcong Dong, et al.

Discussion

Detergent-Triggered Membrane Remodelling Monitored via Intramembrane Fluorescence De-Quenching

Claudia M. F. Andrews, Christopher M. Hofmair, Lauryn Roberts, et al.

Discussion

Self-renewal of neuronal mitochondria through asymmetric division

Tejashree Pradip Waingankar, Camryn Zurita, Angelica E. Lang, et al.

Human single-cell atlas analysis reveals heterogeneous endothelial signaling

Zimo Zhu, Rongbin Zheng, Yang Yu, et al.

Discussion

Stress granules formed during different RNA virus infections show remarkable plasticity and substantial virus-specific differences in their formation and composition

Reto M. Lang, Silvio Steiner, Jenna Kelly, et al.

Discussion

In depth profiling of the cancer proteome from the flowthrough of standard RNA- preparation kits for precision oncology

Filip Mundt Madsen, Annelaura Bach Nielsen, Juanjuan Wang, et al.