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RAD50 promotes DNA repair by homologous recombination and restrains antigenic variation in African trypanosomes

Ann-Kathrin Mehnert, Marco Prorocic, Annick Dujeancourt-Henry, et al.

Selected by 22 April 2020

Jennifer Ann Black

Microbiology

Comparative analyses of two primate species diverged by more than 60 million years show different rates but similar distribution of genome-wide UV repair events

Umit Akkose, Ogulcan Kaya, Laura Lindsey-Boltz, et al.

Selected by 15 April 2020

Kerryn Elliott

Genomics

Evolutionarily diverse LIM domain-containing proteins bind stressed actin filaments through a conserved mechanism

Jonathan D. Winkelman, Caitlin A. Anderson, Cristian Suarez, et al.

AND

Mechanosensing through direct binding of tensed F-actin by LIM domains

Xiaoyu Sun, Donovan Y. Z. Phua, Lucas Axiotakis Jr., et al.

Selected by 15 April 2020

Angika Basant

Cell Biology

Constricted migration contributes to persistent 3D genome structure changes associated with an invasive phenotype in melanoma cells

Rosela Golloshi, Rebeca San Martin, Priyojit Das, et al.

Selected by 02 April 2020

Mariana De Niz

Cancer Biology

Robotic microscopy for everyone: the OpenFlexure Microscope

Joel T. Collins, Joe Knapper, Julian Stirling, et al.

Selected by 27 March 2020

Mariana De Niz

Bioengineering

An asymmetry in the frequency and position of mitosis in the epiblast precedes gastrulation and suggests a role for mitotic rounding in cell delamination during primitive streak epithelial-mesenchymal transition

Evangéline Despin-Guitard, Navrita Mathiah, Matthew Stower, et al.

Selected by 12 March 2020

Claire Simon & Sophie Morgani

Loss of epithelial polarity redirects Notch signaling and triggers a Xrp1 response during neoplastic growth in Drosophila

Rémi Logeay, Charles Géminard, Patrice Lassus, et al.

Selected by 27 February 2020

Sally Lowell

Developmental Biology

Mutational signatures are jointly shaped by DNA damage and repair

Nadezda V Volkova, Bettina Meier, Víctor González-Huici, et al.

Selected by 24 February 2020

Kerryn Elliott

Cancer Biology

Regeneration in the adult Drosophila brain

Crocker, K.L., Marischuk, K., Rimkus, S.A., et al.

Selected by 12 February 2020

Ivana Viktorinová

Neuroscience

Patient-derived ovarian cancer organoids mimic clinical response and exhibit heterogeneous inter- and intrapatient drug responses

Chris J. de Witte, Jose Espejo Valle-Inclan, Nizar Hami, et al.

Selected by 31 December 2019

Zhang-He Goh

Pharmacology and Toxicology

Origin and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages

Calum C. Bain, Douglas A. Gibson, Nicholas Steers, et al.

Selected by 03 December 2019

Connor Rosen

Immunology

Senescence of alveolar stem cells drives progressive pulmonary fibrosis

Changfu Yao, Xiangrong Guan, Gianni Carraro, et al.

Selected by 08 November 2019

Rob Hynds

Cell Biology