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The antimicrobial peptide DGL13K is active against resistant gram-negative bacteria and subinhibitory concentrations stimulate bacterial growth without causing resistance

Sven-Ulrik Gorr, Hunter V. Brigman, Jadyn C. Anderson, et al.

Selected by 17 May 2020

Zhang-He Goh

Discussion

Triclosan depletes the membrane potential in Pseudomonas aeruginosa biofilms inhibiting aminoglycoside induced adaptive resistance

Michael M. Maiden, Christopher M. Waters

Selected by 27 April 2020

Amberley Stephens

Orally Bioavailable Endochin-like Quinolone Carbonate Ester Prodrug Reduces Toxoplasma gondii Brain Cysts

J. Stone Doggett, Tracey Schultz, Alyssa J. Miller, et al.

Selected by 10 April 2020

Zhang-He Goh

Discussion

Combining antibiotics with antivirulence compounds is effective and can reverse selection for antibiotic resistance in Pseudomonas aeruginosa

Chiara Rezzoagli, Martina Archetti, Michael Baumgartner, et al.

Selected by 10 December 2019

Zhang-He Goh

Discussion

Engineering Phage Host-Range and Suppressing Bacterial resistance Through Phage Tail Fiber Mutagenesis

Kevin Yehl, Sébastien Lemire, Andrew C. Yang, et al.

Selected by 27 July 2019

Zhang-He Goh

Discussion

antimicrobials: Discovery, clinical use, and development of resistance

Preprints that describe the discovery of new antimicrobials and any improvements made regarding their clinical use. Includes preprints that detail the factors affecting antimicrobial selection and the development of antimicrobial resistance.

 

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Zhang-He Goh

Using machine learning to guide targeted and locally-tailored empiric antibiotic prescribing in a children's hospital in Cambodia

Mathupanee Oonsivilai, Mo Yin, Nantasit Luangasanatip, et al.

Selected by 22 July 2018

Zhang-He Goh

Discussion

Repurposing the quinoline antibiotic nitroxoline to treat infections caused by the brain-eating amoeba Balamuthia mandrillaris

Matthew T. Laurie, Corin V. White, Hanna Retallack, et al.

Selected by 11 July 2018

Zhang-He Goh

Discussion