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Ageing-associated myelin dysfunction drives amyloid deposition in mouse models of Alzheimer’s disease

Constanze Depp, Ting Sun, Andrew Octavian Sasmita, et al.



Selected by Kristina Kuhbandner

1

Foldamers Reveal and Validate Novel Therapeutic Targets Associated with Toxic α-Synuclein Self-Assembly

Jemil Ahmed, Tessa C. Fitch, Courtney M. Donnelly, et al.



Selected by Joanna Zell

1

Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating other proteins aggregation

Urszula Nowicka, Piotr Chroscicki, Karen Stroobants, et al.



Selected by Eric McGregor

A “spindle and thread”-mechanism unblocks translation of N-terminally disordered proteins

Margit Kaldmäe, Thibault Vosselman, Xueying Zhong, et al.



Selected by Utrecht Protein Folding and Assembly

Suppression of aggregate and amyloid formation by a novel intrinsically disordered region in metazoan Hsp110 chaperones

Unekwu M. Yakubu, Kevin A. Morano



Selected by Utrecht Protein Folding and Assembly

1

Brain deletion of Serf2 shifts amyloid conformation in a mouse model

E. Stroo, L. Janssen, O. Sin, et al.



Selected by Utrecht Protein Folding and Assembly

1

Structure of an infectious mammalian prion

Allison Kraus, Forrest Hoyt, Cindi L. Schwartz, et al.



Selected by Jennifer Ann Black

2

L-bodies are novel RNA-protein condensates driving RNA transport in Xenopus oocytes

Christopher R. Neil, Samantha P. Jeschonek, Sarah E. Cabral, et al.



Selected by Maiko Kitaoka

The WD and linker domains of ATG16L1 required for non-canonical autophagy limit lethal influenza A virus infection at epithelial surfaces

Yingxue Wang, Weijiao Zhang, Matthew Jefferson, et al.



Selected by Kirsty Hooper

1

Skd3 (human CLPB) is a potent mitochondrial protein disaggregase that is inactivated by 3-methylglutaconic aciduria-linked mutations

Ryan R. Cupo, James Shorter



Selected by Tessa Sinnige

1

Oligodendrocyte-derived exosomes promote axonal transport and axonal long-term maintenance

Carsten Frühbeis, Wen Ping Kuo-Elsner, Kerstin Barth, et al.



Selected by Theresa Pohlkamp

1

HSP110 dependent HSP70 disaggregation machinery mediates prion-like propagation of amyloidogenic proteins in metazoa

Jessica Tittelmeier, Carl Alexander Sandhof, Heidrun Maja Ries, et al.



Selected by Tessa Sinnige

1

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