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Mechano-dependent sorbitol accumulation supports biomolecular condensate

Stephanie Torrino, William M Oldham, Andrés R Tejedor, et al.

Selected by 07 September 2023

Teodora Piskova

Cell Biology

Ageing-associated myelin dysfunction drives amyloid deposition in mouse models of Alzheimer’s disease

Constanze Depp, Ting Sun, Andrew Octavian Sasmita, et al.

Selected by 19 August 2021

Kristina Kuhbandner

Neuroscience

Foldamers Reveal and Validate Novel Therapeutic Targets Associated with Toxic α-Synuclein Self-Assembly

Jemil Ahmed, Tessa C. Fitch, Courtney M. Donnelly, et al.

Selected by 05 June 2021

Joanna Zell

Biochemistry

Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating other proteins aggregation

Urszula Nowicka, Piotr Chroscicki, Karen Stroobants, et al.

Selected by 20 May 2021

Eric McGregor

Cell Biology

A “spindle and thread”-mechanism unblocks translation of N-terminally disordered proteins

Margit Kaldmäe, Thibault Vosselman, Xueying Zhong, et al.

Selected by 16 April 2021

Utrecht Protein Folding and Assembly

Biochemistry

Suppression of aggregate and amyloid formation by a novel intrinsically disordered region in metazoan Hsp110 chaperones

Unekwu M. Yakubu, Kevin A. Morano

Selected by 14 April 2021

Utrecht Protein Folding and Assembly

Biochemistry

Brain deletion of Serf2 shifts amyloid conformation in a mouse model

E. Stroo, L. Janssen, O. Sin, et al.

Selected by 06 April 2021

Utrecht Protein Folding and Assembly

Molecular Biology

Structure of an infectious mammalian prion

Allison Kraus, Forrest Hoyt, Cindi L. Schwartz, et al.

Selected by 04 March 2021

Jennifer Ann Black

Biochemistry

L-bodies are novel RNA-protein condensates driving RNA transport in Xenopus oocytes

Christopher R. Neil, Samantha P. Jeschonek, Sarah E. Cabral, et al.

Selected by 28 May 2020

Maiko Kitaoka

Cell Biology

The WD and linker domains of ATG16L1 required for non-canonical autophagy limit lethal influenza A virus infection at epithelial surfaces

Yingxue Wang, Weijiao Zhang, Matthew Jefferson, et al.

Selected by 09 March 2020

Kirsty Hooper

Cell Biology

Skd3 (human CLPB) is a potent mitochondrial protein disaggregase that is inactivated by 3-methylglutaconic aciduria-linked mutations

Ryan R. Cupo, James Shorter

Selected by 13 February 2020

Tessa Sinnige

Biochemistry

Oligodendrocyte-derived exosomes promote axonal transport and axonal long-term maintenance

Carsten Frühbeis, Wen Ping Kuo-Elsner, Kerstin Barth, et al.

Selected by 13 January 2020

Theresa Pohlkamp

Neuroscience
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