Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart
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Mouse-embryo model derived exclusively from embryonic stem cells undergo neurulation and heart development
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Monica Tambalo et al.
Comparative developmental genomics of sex-biased gene expression in early embryogenesis across mammals
Selected by
Carly Guiltinan
Plakoglobin is a mechanoresponsive regulator of naïve pluripotency
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Ilaria Di Meglio
Rapid redistribution and extensive binding of NANOG and GATA6 at shared regulatory elements underlie specification of divergent cell fates
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María Mariner-Faulí
YAP1 Regulates the Self-organized Fate Patterning of hESCs-Derived Gastruloids
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Srivatsava Viswanadha
Reconstructing human early embryogenesis in vitro with pluripotent stem cells
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Martin Estermann
Brazil Nut Effect Drives Pattern Formation in Early Mammalian Embryos
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Sophia Friesen
Generating single-sex litters: development of CRISPR-Cas9 genetic tools to produce all-male offspring
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Martin Estermann
Mechanism of cell polarisation and first lineage segregation in the human embryo
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Grace Lim
Parental genome unification is highly erroneous in mammalian embryos
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Madhuja Samaddar
Physical constraints on early blastomere packings
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Sundar Naganathan
Primate naïve pluripotent stem cells stall in the G1 phase of the cell cycle and differentiate prematurely during embryo colonization
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Pierre Osteil