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Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart

Gianluca Amadei, Charlotte E Handford, Joachim De Jonghe, et al.

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Mouse-embryo model derived exclusively from embryonic stem cells undergo neurulation and heart development

Kasey Y.C. Lau, Hernan Rubinstein, Carlos W. Gantner, et al.

Comparative developmental genomics of sex-biased gene expression in early embryogenesis across mammals

Victorya Richardson, Kai Zhang, Nora Engel, et al.

Plakoglobin is a mechanoresponsive regulator of naïve pluripotency

Timo N. Kohler, Joachim De Jonghe, Anna L. Ellerman, et al.

Rapid redistribution and extensive binding of NANOG and GATA6 at shared regulatory elements underlie specification of divergent cell fates

Joyce J. Thompson, Daniel J. Lee, Apratim Mitra, et al.

YAP1 Regulates the Self-organized Fate Patterning of hESCs-Derived Gastruloids

Servando Giraldez, Eleonora Stronati, Ling Huang, et al.

Reconstructing human early embryogenesis in vitro with pluripotent stem cells

Berna Sozen, Victoria Jorgensen, Meng Zhu, et al.

Brazil Nut Effect Drives Pattern Formation in Early Mammalian Embryos

Zheng Guo, Jie Yao, Xu Zheng, et al.

Generating single-sex litters: development of CRISPR-Cas9 genetic tools to produce all-male offspring

Charlotte Douglas, Valdone Maciulyte, Jasmin Zohren, et al.

Mechanism of cell polarisation and first lineage segregation in the human embryo

Meng Zhu, Marta N. Shahbazi, Angel Martin, et al.

Parental genome unification is highly erroneous in mammalian embryos

Tommaso Cavazza, Antonio Z Politi, Patrick Aldag, et al.

Physical constraints on early blastomere packings

James Giammona, Otger Campàs

Primate naïve pluripotent stem cells stall in the G1 phase of the cell cycle and differentiate prematurely during embryo colonization

Irène Aksoy, Cloé Rognard, Anaïs Moulin, et al.