Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair
Selected by
Pierre Caron
CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity
Selected by
Jessica Chevallier, Pierre Caron
Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis
Selected by
Pierre Caron
EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells
Selected by
Jennifer Ann Black
Therapeutic strategy for spinal muscular atrophy by combining gene supplementation and genome editing
Selected by
Preethi Krishnaraj
BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote replication fork stability and continuous DNA synthesis
Selected by
Pierre Caron
Pin1-promoted SUMOylation of RNF168 restrains its chromatin accumulation
Selected by
Pierre Caron
ATM-dependent formation of a novel chromatin compartment regulates the Response to DNA Double Strand Breaks and the biogenesis of translocations
Selected by
Jennifer Ann Black
Drag-and-drop genome insertion without DNA cleavage with CRISPR-directed integrases
Selected by
Louise Moyle et al.
Two redundant ubiquitin-dependent pathways of BRCA1 localization to DNA damage sites
Selected by
Giuseppina D'Alessandro
Neuronal Enhancers are Hotspots For DNA Single-Strand Break Repair
Selected by
Giuseppina D'Alessandro, Sree Rama Chaitanya
EccDNA formation is dependent on MMEJ, repressed by c-NHEJ pathway, and stimulated by DNA double-strand break
Selected by
Sree Rama Chaitanya