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Modeling transcriptional profiles of gene perturbation with a deep neural network

Wenke Liu, Xuya Wang, D R Mani, et al.

Selected by Raquel Moya

Nanos2+ cells give rise to germline and somatic lineages in the sea anemone Nematostella vectensis

Andreas Denner, Julia Steger, Alexander Ries, et al.

Selected by Isabella Cisneros

Single-cell epigenomic reconstruction of developmental trajectories in human neural organoid systems from pluripotency

Fides Zenk, Jonas Simon Fleck, Sophie Martina Johanna Jansen, et al.

Selected by Manuel Lessi

2D and 3D multiplexed subcellular profiling of nuclear instability in human cancer

Shannon Coy, Brian Cheng, Jong Suk Lee, et al.

Selected by Jade Chan

The brittle star genome illuminates the genetic basis of animal appendage regeneration

Elise Parey, Olga Ortega-Martinez, Jérôme Delroisse, et al.

Selected by Isabella Cisneros

Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair

Marieke R. Wensveen, Aditya A. Dixit, Serafin U. Colmenares, et al.

Selected by Pierre Caron

Multi-pass, single-molecule nanopore reading of long protein strands with single-amino acid sensitivity

Keisuke Motone, Daphne Kontogiorgos-Heintz, Jasmine Wee, et al.

Selected by Benjamin Dominik Maier, Samantha Seah

Inference of drug off-target effects on cellular signaling using Interactome-Based Deep Learning

Nikolaos Meimetis, Douglas A. Lauffenburger, Avlant Nilsson

Selected by Benjamin Dominik Maier

The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity

Hasan Mamar, Roberta Fajka-Boja, Mónika Mórocz, et al.

Selected by Audrey Noireterre

Digitize your Biology! Modeling multicellular systems through interpretable cell behavior

Jeanette A.I. Johnson, Genevieve L. Stein-O’Brien, Max Booth, et al.

Selected by Benjamin Dominik Maier et al.

Metabolomic profiling reveals effects of marein on energy metabolism in HepG2 cells

Baoping Jiang, Liang Le,, Keping Hu, et al.

Selected by Hellen Costa, Marcus Oliveira

Ancient origins of complex neuronal genes

Matthew J. McCoy, Andrew Z. Fire

Selected by Preethi Krishnaraj, Chee Kiang Ewe