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2D and 3D multiplexed subcellular profiling of nuclear instability in human cancer

Shannon Coy, Brian Cheng, Jong Suk Lee, et al.

Selected by 22 December 2023

Jade Chan

Cancer Biology

The brittle star genome illuminates the genetic basis of animal appendage regeneration

Elise Parey, Olga Ortega-Martinez, Jérôme Delroisse, et al.

Selected by 16 December 2023

Isabella Cisneros

Evolutionary Biology

Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair

Marieke R. Wensveen, Aditya A. Dixit, Serafin U. Colmenares, et al.

Selected by 15 December 2023

Pierre Caron

Molecular Biology

Multi-pass, single-molecule nanopore reading of long protein strands with single-amino acid sensitivity

Keisuke Motone, Daphne Kontogiorgos-Heintz, Jasmine Wee, et al.

Selected by 04 December 2023

Benjamin Dominik Maier, Samantha Seah

Molecular Biology

Inference of drug off-target effects on cellular signaling using Interactome-Based Deep Learning

Nikolaos Meimetis, Douglas A. Lauffenburger, Avlant Nilsson

Selected by 29 November 2023

Benjamin Dominik Maier

Bioinformatics

The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity

Hasan Mamar, Roberta Fajka-Boja, Mónika Mórocz, et al.

Selected by 14 November 2023

Audrey Noireterre

Cancer Biology

Digitize your Biology! Modeling multicellular systems through interpretable cell behavior

Jeanette A.I. Johnson, Genevieve L. Stein-O’Brien, Max Booth, et al.

Selected by 08 November 2023

Benjamin Dominik Maier et al.

Systems Biology

Metabolomic profiling reveals effects of marein on energy metabolism in HepG2 cells

Baoping Jiang, Liang Le,, Keping Hu, et al.

Selected by 26 October 2023

Hellen Costa, Marcus Oliveira

Biochemistry

Ancient origins of complex neuronal genes

Matthew J. McCoy, Andrew Z. Fire

Selected by 23 October 2023

Preethi Krishnaraj, Chee Kiang Ewe

Evolutionary Biology

Tardigrades dramatically upregulate DNA repair pathway genes in response to ionizing radiation

Courtney M. Clark-Hachtel, Jonathan D. Hibshman, Tristan De Buysscher, et al.

Selected by 18 October 2023

Isabella Cisneros

Genomics

The genome of the colonial hydroid Hydractinia reveals their stem cells utilize a toolkit of evolutionarily shared genes with all animals

Christine E. Schnitzler, E. Sally Chang, Justin Waletich, et al.

Selected by 19 September 2023

Isabella Cisneros

Developmental Biology

CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity

Madison B. Adolph, Atharv S. Garje, Swati Balakrishnan, et al.

Selected by 06 September 2023

Jessica Chevallier, Pierre Caron

Cell Biology