Search results

CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity

Madison B. Adolph, Atharv S. Garje, Swati Balakrishnan, et al.

Selected by 06 September 2023

Jessica Chevallier, Pierre Caron

Discussion

Similarity metric learning on perturbational datasets improves functional identification of perturbations

Ian Smith, Petr Smirnov, Benjamin Haibe-Kains

Selected by 17 August 2023

Benjamin Dominik Maier, Anna Foix Romero

A transposase-derived gene required for human brain development

Luz Jubierre Zapater, Elias Rodriguez-Fos, Merce Planas-Felix, et al.

Selected by 06 July 2023

Amanda Ivanoff

Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis

Camille Gelot, Marton Tibor Kovacs, Simona Miron, et al.

Selected by 05 June 2023

Pierre Caron

Discussion

Biologically informed NeuralODEs for genome-wide regulatory dynamics

Intekhab Hossain, Viola Fanfani, John Quackenbush, et al.

Selected by 31 May 2023

Benjamin Dominik Maier

Susceptible bacteria survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance

Marinelle Rodrigues, Parastoo Sabaeifard, Muhammed Sadik Yildiz, et al.

Selected by 16 May 2023

UofA IMB565

EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells

B. van de Kooij, A. Schreuder, R.S. Pavani, et al.

Selected by 15 May 2023

Jennifer Ann Black

Inhibition of Cellular MEK/ERK Signaling Suppresses Murine Papillomavirus Type 1 Replicative Activities and Promotes Tumor Regression

Adrian J. Luna, Jesse M. Young, Rosa T. Sterk, et al.

Selected by 14 May 2023

Yvonne Xinyi Lim

Complete male-to-female sex reversal in XY mice lacking the miR-17∼92 cluster

Alicia Hurtado, Irene Mota-Gómez, Miguel Lao, et al.

Selected by 07 May 2023

Martin Estermann

Therapeutic strategy for spinal muscular atrophy by combining gene supplementation and genome editing

Fumiyuki Hatanaka, Keiichiro Suzuki, Kensaku Shojima, et al.

Selected by 03 May 2023

Preethi Krishnaraj

Discussion

Phospho-seq: Integrated, multi-modal profiling of intracellular protein dynamics in single cells

John D. Blair, Austin Hartman, Fides Zenk, et al.

Selected by 19 April 2023

Benjamin Dominik Maier

Alumni

Mitotic heritability of DNA methylation at intermediately methylated sites is imprecise

Amir D. Hay, Noah J. Kessler, Daniel Gebert, et al.

Selected by 24 March 2023

Samantha Seah et al.