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A pharmacokinetic-pharmacodynamic assessment of the hepatic and bone-marrow toxicities of the new trypanoside fexinidazole

James Andrew Watson, Nathalie Strub-Wourgraft, Antoine Tarral, et al.

A direct selection strategy for isolating aptamers with pH-sensitive binding activity

Chelsea K L Gordon, Michael Eisenstein, H T Soh

Discussion

Incorporation of doxorubicin in different polymer nanoparticles and their anti-cancer activity

S Pieper, Hannah Onafuye, Dennis Mulac, et al.

Discussion

PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection

Catherine M Buckley, Victoria L Heath, Aurelie Gueho, et al.

The cytoskeleton as a smart composite material: A unified pathway linking microtubules, myosin-II filaments and integrin adhesions

Nisha Mohd Rafiq, Yukako Nishimura, Sergey V. Plotnikov, et al.

Discussion

Atropselective Oxidation of 2,2',3,3',4,6'-Hexachlorobiphenyl (PCB 132) to Hydroxylated Metabolites by Human liver Microsomes: Involvement of Arene Oxide Intermediates

Eric Uwimana, Xueshu Li, Coby Yeung, et al.

LADL: Light-activated dynamic looping for endogenous gene expression control

Mayuri Rege, Ji Hun Kim, Jacqueline Valeri, et al.

Discussion

Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages is necessary for functional spinal cord regeneration in zebrafish

Themistoklis M. Tsarouchas, Daniel Wehner, Leonardo Cavone, et al.

ER-to-Golgi trafficking of procollagen in the absence of large carriers.

Janine McCaughey, Nicola Stevenson, Stephen Cross, et al.

Targeting light-gated chloride channels to neuronal somatodendritic domain reduces their excitatory effect in the axon

Jessica Messier, Hongmei Chen, Zhao-Lin Cai, et al.

AND

High-efficiency optogenetic silencing with soma-targeted anion-conducting channelrhodopsins

Mathias Mahn, Lihi Gibor, Katayun Cohen-Kashi Malina, et al.

Cerebellar contribution to preparatory activity in motor neocortex

Francois Pierre Chabrol, Antonin Blot, Thomas D Mrsic-Flogel

A novel mechanism of gland formation in zebrafish involving transdifferentiation of renal epithelial cells and live cell extrusion

Richard W Naylor, Alan J Davidson