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Self-reporting transposons enable simultaneous readout of gene expression and transcription factor binding in single cells

Arnav Moudgil, Michael N Wilkinson, Xuhua Chen, et al.

SLC19A1 is a cyclic dinucleotide transporter

Rutger Luteijn, Shivam Zaver, Benjamin G Gowen, et al.

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SLC19A1 is an importer of the immunotransmitter cGAMP

Anthony F. Cordova, Christopher Ritchie, Gaelen T. Hess, et al.

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2'3'-cGAMP is an immunotransmitter produced by cancer cells and regulated by ENPP1

Jacqueline A Carozza, Volker Boehnert, Kelsey E Shaw, et al.

Minimal membrane interactions conferred by Rheb C-terminal farnesylation are essential for mTORC1 activation

Shawn M Ferguson, Brittany Angarola

Regulation of modulatory cell activity across olfactory structures in Drosophila melanogaster

Xiaonan Zhang, Kaylynn Coates, Andrew Dacks, et al.

Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells

Jayashree Chadchankar, Victoria Korboukh, Peter Doig, et al.

A metabolic switch from OXPHOS to glycolysis is essential for cardiomyocyte proliferation in the regenerating heart

Hessel Honkoop, Dennis de Bakker, Alla Aharonov, et al.

Variability of bacterial behavior in the mammalian gut captured using a growth-linked single-cell synthetic gene oscillator

David T Riglar, David L Richmond, Laurent Potvin-Trottier, et al.

A conserved MFS orchestrates a subset of O-glycosylation to facilitate macrophage dissemination and tissue invasion

Katarina Valoskova, Julia Biebl, Marko Roblek, et al.

MRE11-RAD50-NBS1 activates Fanconi Anemia R-loop suppression at transcription-replication conflicts

Emily Yun-Chia Chang, James P Wells, Shu-Huei Tsai, et al.

A Rap1 binding site and lipid-dependent helix in talin F1 domain cooperate in integrin activation

Alexandre Gingras, Frederic Lagarrigue, Monica Cuevas, et al.

Single cell RNA-Seq reveals distinct stem cell populations that drive sensory hair cell regeneration in response to loss of Fgf and Notch signaling

Mark E. Lush, Daniel C. Diaz, Nina Koenecke, et al.

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Distinct progenitor populations mediate regeneration in the zebrafish lateral line.

Eric D Thomas, David Raible

Embryo geometry drives formation of robust signaling gradients through receptor localization

Zhechun Zhang, Steven Zwick, Ethan Loew, et al.