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Generating single-sex litters: development of CRISPR-Cas9 genetic tools to produce all-male offspring

Charlotte Douglas, Valdone Maciulyte, Jasmin Zohren, et al.

PACAP induces light aversion in mice by an inheritable mechanism independent of CGRP

Adisa Kuburas, Bianca N. Mason, Benjamin Hing, et al.

Toll-like receptor 4 is activated by platinum and contributes to cisplatin-induced ototoxicity

Ghazal Babolmorad, Asna Latif, Niall M. Pollock, et al.

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Application of the in vivo oxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity

Francisco Inesta-Vaquera, Panida Navasumrit, Colin J. Henderson, et al.

Electron Transfer from Cytochrome P450 Reductase to Cytochrome P450: Towards a Structural and Dynamic Understanding

Goutam Mukherjee, Prajwal P. Nandekar, Rebecca C. Wade

Systematic analysis of protein targets associated with adverse events of drugs from clinical trials and post-marketing reports

Ines A. Smit, Avid M. Afzal, Chad H. G. Allen, et al.

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Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia

Hongbin Wan, Gianluca Selvaggio, Robert A. Pearlstein

A hydraulic instability drives the cell death decision in the nematode germline

N. T. Chartier, A. Mukherjee, J. Pfanzelter, et al.

Sexually Dimorphic DNA Damage Responses and Mutation Avoidance in the Mouse Germline

Jordana C. Bloom, John C. Schimenti

Stem-cell niche self-restricts the signaling range via receptor-ligand degradation

Sophia Ladyzhets, Matthew Antel, Taylor Simao, et al.

Genetic Developmental Timing Revealed by Inter-Species Transplantations in Fish

Jana Franziska Fuhrmann, Lorena Buono, Juan Ramón Martinez Morales, et al.

Changing and stable chromatin accessibility supports transcriptional overhaul during neural stem cell activation

Sun Y. Maybury-Lewis, Abigail K. Brown, Mitchell Yeary, et al.

Mutual Potentiation of Plant Immunity by Cell-surface and Intracellular Receptors

Bruno Pok Man Ngou, Hee-Kyung Ahn, Pingtao Ding, et al.

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Pattern-recognition receptors are required for NLR-mediated plant immunity

Minhang Yuan, Zeyu Jiang, Guozhi Bi, et al.

Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes

Jiwen Li, Lin Pan, Marlesa I. Godoy, et al.