Search results

Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair

Marieke R. Wensveen, Aditya A. Dixit, Serafin U. Colmenares, et al.

Selected by 15 December 2023

Pierre Caron

Tardigrades dramatically upregulate DNA repair pathway genes in response to ionizing radiation

Courtney M. Clark-Hachtel, Jonathan D. Hibshman, Tristan De Buysscher, et al.

Selected by 18 October 2023

Isabella Cisneros

Discussion

A transposase-derived gene required for human brain development

Luz Jubierre Zapater, Elias Rodriguez-Fos, Merce Planas-Felix, et al.

Selected by 06 July 2023

Amanda Ivanoff

Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis

Camille Gelot, Marton Tibor Kovacs, Simona Miron, et al.

Selected by 05 June 2023

Pierre Caron

Discussion

Therapeutic strategy for spinal muscular atrophy by combining gene supplementation and genome editing

Fumiyuki Hatanaka, Keiichiro Suzuki, Kensaku Shojima, et al.

Selected by 03 May 2023

Preethi Krishnaraj

Discussion

Pin1-promoted SUMOylation of RNF168 restrains its chromatin accumulation

Anoop Singh Chauhan, Alexander J. Garvin, Mohammed Jamshad, et al.

Selected by 20 June 2022

Pierre Caron

Discussion

Drag-and-drop genome insertion without DNA cleavage with CRISPR-directed integrases

Eleonora I. Ioannidi, Matthew T. N. Yarnall, Cian Schmitt-Ulms, et al.

Selected by 15 December 2021

Louise Moyle et al.

Saturation variant interpretation using CRISPR prime editing

Steven Erwood, Teija M.I. Bily, Jason Lequyer, et al.

Selected by 20 October 2021

Jeffrey Calhoun

EccDNA formation is dependent on MMEJ, repressed by c-nhej pathway, and stimulated by DNA double-strand break

Teressa Paulsen, Pumoli Malapati, Rebeka Eki, et al.

Selected by 05 January 2021

Sree Rama Chaitanya

Severe immunodeficiency in mice lacking DNA repair factors XLF and Mri

Sergio Castañeda-Zegarra, Qindong Zhang, Amin Alirezaylavasani, et al.

Selected by 27 July 2020

Jennifer Ann Black

Discussion

Hyperactive end joining repair mediates resistance to DNA damaging therapy in p53-deficient cells

Rashmi J. Kumar, Hui Xiao Chao, Victoria R. Roberts, et al.

Selected by 24 June 2020

Matthew Burke

Discussion

Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance

Ruben Schep, Eva Brinkman, Christ Leemans, et al.

Selected by 11 June 2020

Katie Weiner